CD137 Is Induced by the CD40 Signal on Chronic Lymphocytic Leukemia B Cells and Transduces the Survival Signal via NF-κB Activation

ERK-Dependent Bim Modulation Downstream of the 4-1BB-TRAF1 Signaling Axis Is a Critical Mediator of CD8 T Cell Survival In Vivo

(2014) L. Sabbagh et al.   JOURNAL OF IMMUNOLOGY

CD137 Induces Proliferation of Murine Hematopoietic Progenitor Cells and Differentiation to Macrophages

(2014) D. Jiang et al.   JOURNAL OF IMMUNOLOGY

The microenvironment in follicular lymphoma

(2011) Daphne de Jong et al.   BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY

4-1BB ligand modulates direct and Rituximab-induced NK-cell reactivity in chronic lymphocytic leukemia

(2011) Corina Buechele et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The functional in vitro response to CD40 ligation reflects a different clinical outcome in patients with chronic lymphocytic leukemia

(2011) C Scielzo et al.   LEUKEMIA

Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion

(2009) R. Houot et al.   BLOOD

CD137 Promotes Proliferation and Survival of Human B Cells

(2009) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

4-1BB Functions As a Survival Factor in Dendritic Cells

(2009) B. K. Choi et al.   JOURNAL OF IMMUNOLOGY

c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches

(2008) D. Y. H. Hallaert et al.   BLOOD

Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines

(2008) M. Hallek et al.   BLOOD

Fc-dependent expression of CD137 on human NK cells: insights into "agonistic" effects of anti-CD137 monoclonal antibodies

(2008) W. Lin et al.   BLOOD

CD137 Is Expressed in Human Atherosclerosis and Promotes Development of Plaque Inflammation in Hypercholesterolemic Mice

(2008) Peder S. Olofsson et al.   CIRCULATION

CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response

(2008) Undine Lippert et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The promise of 4-1BB (CD137)-mediated immunomodulation and the immunotherapy of cancer

(2008) David H. Lynch   IMMUNOLOGICAL REVIEWS

Novel Insights in Chronic Lymphocytic Leukemia: Are We Getting Closer to Understanding the Pathogenesis of the Disease?

(2008) Federico Caligaris-Cappio et al.   JOURNAL OF CLINICAL ONCOLOGY

Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells

(2008) Seung-Woo Lee et al.   NATURE IMMUNOLOGY

Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a

(2008) T. Fukuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induction of Proliferation and Monocytic Differentiation of Human CD34+Cells by CD137 Ligand Signaling

(2008) Dongsheng Jiang et al.   STEM CELLS

Multi-layered action mechanisms of CD137 (4-1BB)-targeted immunotherapies

(2008) Ignacio Melero et al.   TRENDS IN PHARMACOLOGICAL SCIENCES