Normalization of Tumor Microenvironment by Neem Leaf Glycoprotein Potentiates Effector T Cell Functions and Therapeutically Intervenes in the Growth of Mouse Sarcoma

Neem Leaf Glycoprotein Activates CD8+ T Cells to Promote Therapeutic Anti-Tumor Immunity Inhibiting the Growth of Mouse Sarcoma

(2013) Atanu Mallick et al.   PLoS One

Neem leaf glycoprotein is nontoxic to physiological functions of Swiss mice and Sprague Dawley rats: Histological, biochemical and immunological perspectives

(2012) Atanu Mallick et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antitumor Activity of T Cells Generated from Lymph Nodes Draining the SEA-expressing Murine B16 Melanoma and Secondarily Activated with Dendritic Cells

(2012) Jiyun Yu et al.   International Journal of Biological Sciences

Dual Roles of Immune Cells and Their Factors in Cancer Development and Progression

(2012) Brian F. Zamarron et al.   International Journal of Biological Sciences

Anticancer biology ofAzadirachta indicaL (neem): A mini review

(2011) Rajkumar Paul et al.   CANCER BIOLOGY & THERAPY

Neem leaf glycoprotein inhibits CD4+CD25+Foxp3+Tregs to restrict murine tumor growth

(2011) Tathagata Chakraborty et al.   Immunotherapy

Restoration of dysregulated CC chemokine signaling for monocyte/macrophage chemotaxis in head and neck squamous cell carcinoma patients by neem leaf glycoprotein maximizes tumor cell cytotoxicity

(2010) Krishnendu Chakraborty et al.   Cellular & Molecular Immunology

Enrichment of CCR6+Foxp3+ regulatory T cells in the tumor mass correlates with impaired CD8+ T cell function and poor prognosis of breast cancer

(2010) Lin Xu et al.   CLINICAL IMMUNOLOGY

Tumors as Organs: Complex Tissues that Interface with the Entire Organism

(2010) Mikala Egeblad et al.   DEVELOPMENTAL CELL

Neem leaf glycoprotein enhances carcinoembryonic antigen presentation of dendritic cells to T and B cells for induction of anti-tumor immunity by allowing generation of immune effector/memory response

(2010) Koustav Sarkar et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Induction of type 1 cytokines during neem leaf glycoprotein assisted carcinoembryonic antigen vaccination is associated with nitric oxide production

(2009) Koustav Sarkar et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Neem leaf glycoprotein matures myeloid derived dendritic cells and optimizes anti-tumor T cell functions

(2009) Shyamal Goswami et al.   VACCINE

IL-2 and IL-21 confer opposing differentiation programs to CD8+ T cells for adoptive immunotherapy

(2008) C. S. Hinrichs et al.   BLOOD

Cancer and the tumor microenvironment: a review of an essential relationship

(2008) Flaubert Mbeunkui et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

CD8+ T-Cell Responses against Hemoglobin-  Prevent Solid Tumor Growth

(2008) H. Komita et al.   CANCER RESEARCH

Molecular regulation of T-cell anergy

(2008) Yan Zheng et al.   EMBO REPORTS

The tumor microenvironment and its contribution to tumor evolution toward metastasis

(2008) Girieca Lorusso et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Neem leaf glycoprotein directs T-bet–associated type 1 immune commitment

(2008) Anamika Bose et al.   HUMAN IMMUNOLOGY

Neem Leaf Glycoprotein Induces Perforin-mediated Tumor Cell Killing by T and NK Cells Through Differential Regulation of IFNγ Signaling

(2008) Anamika Bose et al.   JOURNAL OF IMMUNOTHERAPY

Neem leaf glycoprotein helps to generate carcinoembryonic antigen specific anti-tumor immune responses utilizing macrophage-mediated antigen presentation

(2008) Koustav Sarkar et al.   VACCINE

Neem leaf glycoprotein restores the impaired chemotactic activity of peripheral blood mononuclear cells from head and neck squamous cell carcinoma patients by maintaining CXCR3/CXCL10 balance

(2007) Krishnendu Chakraborty et al.   INTERNATIONAL IMMUNOPHARMACOLOGY