Enhanced Immune Response and Protective Effects of Nano-chitosan-based DNA Vaccine Encoding T Cell Epitopes of Esat-6 and FL against Mycobacterium Tuberculosis Infection

Mucosally Delivered Dendritic Cells Activate T Cells Independently of IL-12 and Endogenous APCs

(2014) S. McCormick et al.   JOURNAL OF IMMUNOLOGY

Nanoparticle-based adjuvant for enhanced protective efficacy of DNA vaccine Ag85A-ESAT-6-IL-21 against Mycobacterium tuberculosis infection

(2012) Fangliu Yu et al.   Nanomedicine-Nanotechnology Biology and Medicine

Adjuvanted, antigen loaded N-trimethyl chitosan nanoparticles for nasal and intradermal vaccination: Adjuvant- and site-dependent immunogenicity in mice

(2011) Suzanne M. Bal et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chitosan Microparticles and Nanoparticles as Biocompatible Delivery Vehicles for Peptide and Protein-Based Immunocontraceptive Vaccines

(2011) Brendon Y. Chua et al.   MOLECULAR PHARMACEUTICS

Distinct polyfunctional CD4+ T cell responses to BCG, ESAT-6 and CFP-10 in tuberculous pleurisy

(2011) Li Li et al.   TUBERCULOSIS

Improved immune responses in mice using the novel chitosan adjuvant ViscoGel, with a Haemophilus influenzae type b glycoconjugate vaccine

(2011) Theresa Neimert-Andersson et al.   VACCINE

Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in volunteers with previous BCG vaccination or tuberculosis infection

(2011) Jaap T. van Dissel et al.   VACCINE

Early Secreted Antigen ESAT-6 of Mycobacterium tuberculosis Promotes Protective T Helper 17 Cell Responses in a Toll-Like Receptor-2-dependent Manner

(2011) Samit Chatterjee et al.   PLoS Pathogens

Screening of Predicted Secreted Antigens from Mycobacterium bovis Reveals the Immunodominance of the ESAT-6 Protein Family

(2010) G. J. Jones et al.   INFECTION AND IMMUNITY

New vaccines for tuberculosis

(2010) Stefan HE Kaufmann et al.   LANCET

Novel recombinant BCG coexpressing Ag85B, ESAT-6 and mouse TNF-α induces significantly enhanced cellular immune and antibody responses in C57BL/6 mice

(2010) Hongbo Shen et al.   MICROBIOLOGY AND IMMUNOLOGY

Improved Immunogenicity of Recombinant Mycobacterium bovis Bacillus Calmette-Guérin Strains Expressing Fusion Protein Ag85A-ESAT-6 of Mycobacterium tuberculosis

(2010) Y. H. Deng et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

The Population Dynamics and Control of Tuberculosis

(2010) C. Dye et al.   SCIENCE

Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

(2010) Jaap T. van Dissel et al.   VACCINE

Accelerated induction of mycobacterial antigen-specific CD8+T cells in theMycobacterium tuberculosis-infected lung by subcutaneous vaccination withMycobacterium bovisbacille Calmette-Guérin

(2009) Dilara Begum et al.   IMMUNOLOGY

Mechanistic study of the adjuvant effect of biodegradable nanoparticles in mucosal vaccination

(2009) Bram Slütter et al.   JOURNAL OF CONTROLLED RELEASE

Quality and Vaccine Efficacy of CD4+ T Cell Responses Directed to Dominant and Subdominant Epitopes in ESAT-6 from Mycobacterium tuberculosis

(2009) C. S. Aagaard et al.   JOURNAL OF IMMUNOLOGY

A novel DNA vaccine containing multiple TB-specific epitopes cast in a natural structure elicits enhanced Th1 immunity compared with BCG

(2009) Haifeng Gao et al.   MICROBIOLOGY AND IMMUNOLOGY

Identification of proteins from tuberculin purified protein derivative (PPD) by LC-MS/MS

(2009) Sibele Borsuk et al.   TUBERCULOSIS

Augmented humoral and cellular immune response of hepatitis B virus DNA vaccine by micro-needle vaccination using Flt3L as an adjuvant

(2009) Qi Zhou et al.   VACCINE

Recombinant DNA vaccine of the early secreted antigen ESAT-6 by Mycobacterium tuberculosis and Flt3 ligand enhanced the cell-mediated immunity in mice

(2008) Juan Xu et al.   VACCINE

Plasmid DNA loaded chitosan nanoparticles for nasal mucosal immunization against hepatitis B

(2007) Kapil Khatri et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A protein linkage map of the ESAT-6 secretion system 1 (ESX-1) of Mycobacterium tuberculosis

(2007) Janka Teutschbein et al.   MICROBIOLOGICAL RESEARCH