Nicotinic Acid Receptor GPR109A Is Down-Regulated in Human Macrophage-Derived Foam Cells

Modulating peroxisome proliferator–activated receptors for therapeutic benefit? Biology, clinical experience, and future prospects

(2012) Robert S. Rosenson et al.   AMERICAN HEART JOURNAL

Anti-Inflammatory Effects of Nicotinic Acid in Human Monocytes Are Mediated by GPR109A Dependent Mechanisms

(2012) Janet E. Digby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

THE ROLE OF NIACIN IN THE AFTERMATH OF AIM-HIGH: A META-ANALYSIS

(2012) Paul Michael Lavigne et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The cellular and signaling networks linking the immune system and metabolism in disease

(2012) Olivia Osborn et al.   NATURE MEDICINE

Niacin in Cardiovascular Disease: Recent Preclinical and Clinical Developments

(2011) Janet E. Digby et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: Findings from in vitro and ex vivo studies

(2011) Hideki Ozasa et al.   ATHEROSCLEROSIS

Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques

(2011) Jonathan E. Feig et al.   CIRCULATION

The PPAR-RXR Transcriptional Complex in the Vasculature

(2011) Jorge Plutzky   CIRCULATION RESEARCH

Niacin: The Evidence, Clinical Use, and Future Directions

(2011) Todd C. Villines et al.   Current Atherosclerosis Reports

Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells

(2011) Martina Lukasova et al.   JOURNAL OF CLINICAL INVESTIGATION

Niacin in Patients with Low HDL Cholesterol Levels Receiving Intensive Statin Therapy

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)

(2011) S. Offermanns et al.   PHARMACOLOGICAL REVIEWS

A simple and sensitive enzymatic method for cholesterol quantification in macrophages and foam cells

(2010) Peggy Robinet et al.   JOURNAL OF LIPID RESEARCH

Chronicin vitroketosis is neuroprotective but not anti-convulsant

(2010) Marina Samoilova et al.   JOURNAL OF NEUROCHEMISTRY

The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6–HDL and LDL Treatment Strategies in Atherosclerosis)

(2010) Todd C. Villines et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin

(2009) Janet E. Digby et al.   ATHEROSCLEROSIS

Meta-analysis of the effect of nicotinic acid alone or in combination on cardiovascular events and atherosclerosis

(2009) Eric Bruckert et al.   ATHEROSCLEROSIS

GPR109A Is a G-protein-Coupled Receptor for the Bacterial Fermentation Product Butyrate and Functions as a Tumor Suppressor in Colon

(2009) M. Thangaraju et al.   CANCER RESEARCH

β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice

(2009) Robert W. Walters et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of High-Dose Modified-Release Nicotinic Acid on Atherosclerosis and Vascular Function

(2009) Justin M.S. Lee et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Extended-Release Niacin or Ezetimibe and Carotid Intima–Media Thickness

(2009) Allen J. Taylor et al.   NEW ENGLAND JOURNAL OF MEDICINE

Niacin Promotes Cholesterol Efflux through Stimulation of the PPARγ-LXRα-ABCA1 Pathway in 3T3-L1 Adipocytes

(2009) Zhi-Hong Wu et al.   PHARMACOLOGY

Regulation of PPARγ function by TNF-α

(2008) Jianping Ye   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS