Modulating Gradients in Regulatory Signals within Mesenchymal Stem Cell Seeded Hydrogels: A Novel Strategy to Engineer Zonal Articular Cartilage

Cell–matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure

(2012) A.J. Steward et al.   Acta Biomaterialia

Engineering osteochondral constructs through spatial regulation of endochondral ossification

(2012) Eamon J. Sheehy et al.   Acta Biomaterialia

European Society of Biomechanics S.M. Perren Award 2012: The external mechanical environment can override the influence of local substrate in determining stem cell fate

(2012) Stephen D. Thorpe et al.   JOURNAL OF BIOMECHANICS

The role of the superficial region in determining the dynamic properties of articular cartilage

(2012) A.R. Gannon et al.   OSTEOARTHRITIS AND CARTILAGE

The Role of Environmental Factors in Regulating the Development of Cartilaginous Grafts Engineered Using Osteoarthritic Human Infrapatellar Fat Pad–Derived Stem Cells

(2012) Yurong Liu et al.   TISSUE ENGINEERING PART A

Continuous and Uninterrupted Oxygen Tension Influences the Colony Formation and Oxidative Metabolism of Human Mesenchymal Stem Cells

(2012) Girish Pattappa et al.   TISSUE ENGINEERING PART C-METHODS

Oxygen tension regulates the osteogenic, chondrogenic and endochondral phenotype of bone marrow derived mesenchymal stem cells

(2011) Eamon J. Sheehy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Engineering articular cartilage with spatially-varying matrix composition and mechanical properties from a single stem cell population using a multi-layered hydrogel

(2011) Lonnissa H. Nguyen et al.   BIOMATERIALS

Creation of an in vitro microenvironment to enhance human fetal synovium-derived stem cell chondrogenesis

(2011) Jingting Li et al.   CELL AND TISSUE RESEARCH

Dynamic loading of immature epiphyseal cartilage pumps nutrients out of vascular canals

(2011) Michael B. Albro et al.   JOURNAL OF BIOMECHANICS

The effect of cyclic hydrostatic pressure on the functional development of cartilaginous tissues engineered using bone marrow derived mesenchymal stem cells

(2011) E.G. Meyer et al.   Journal of the Mechanical Behavior of Biomedical Materials

Chondrocytes and bone marrow-derived mesenchymal stem cells undergoing chondrogenesis in agarose hydrogels of solid and channelled architectures respond differentially to dynamic culture conditions

(2011) Eamon J. Sheehy et al.   Journal of Tissue Engineering and Regenerative Medicine

Temporal and Spatial Changes in Cartilage-Matrix-Specific Gene Expression in Mesenchymal Stem Cells in Response to Dynamic Compression

(2011) Matthew G. Haugh et al.   TISSUE ENGINEERING PART A

Dynamic Tensile Loading Improves the Functional Properties of Mesenchymal Stem Cell-Laden Nanofiber-Based Fibrocartilage

(2011) Brendon M. Baker et al.   TISSUE ENGINEERING PART A

The Influence of Construct Scale on the Composition and Functional Properties of Cartilaginous Tissues Engineered Using Bone Marrow-Derived Mesenchymal Stem Cells

(2011) Conor T. Buckley et al.   TISSUE ENGINEERING PART A

Dynamic Compressive Loading Enhances Cartilage Matrix Synthesis and Distribution and Suppresses Hypertrophy in hMSC-Laden Hyaluronic Acid Hydrogels

(2011) Liming Bian et al.   TISSUE ENGINEERING PART A

The Response of Bone Marrow-Derived Mesenchymal Stem Cells to Dynamic Compression Following TGF-β3 Induced Chondrogenic Differentiation

(2010) Stephen D. Thorpe et al.   ANNALS OF BIOMEDICAL ENGINEERING

Unique biomaterial compositions direct bone marrow stem cells into specific chondrocytic phenotypes corresponding to the various zones of articular cartilage

(2010) Lonnissa H. Nguyen et al.   BIOMATERIALS

The role of mechanical signals in regulating chondrogenesis and osteogenesis of mesenchymal stem cells

(2010) Daniel J. Kelly et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

A Large Strain Material Model for Soft Tissues With Functionally Graded Properties

(2010) Uwe-Jens Görke et al.   JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME

Low oxygen tension is a more potent promoter of chondrogenic differentiation than dynamic compression

(2010) Eric G. Meyer et al.   JOURNAL OF BIOMECHANICS

The metabolism of human mesenchymal stem cells during proliferation and differentiation

(2010) Girish Pattappa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The potential of stem cells in the treatment of knee cartilage defects

(2010) Wasim S. Khan et al.   KNEE

Oxygen tension differentially regulates the functional properties of cartilaginous tissues engineered from infrapatellar fat pad derived MSCs and articular chondrocytes

(2010) C.T. Buckley et al.   OSTEOARTHRITIS AND CARTILAGE

Improving Chondrogenesis: Potential and Limitations of SOX9 Gene Transfer and Mechanical Stimulation for Cartilage Tissue Engineering

(2010) Laszlo Kupcsik et al.   TISSUE ENGINEERING PART A

Tensile Loading Modulates Bone Marrow Stromal Cell Differentiation and the Development of Engineered Fibrocartilage Constructs

(2010) John T. Connelly et al.   TISSUE ENGINEERING PART A

Impact of oxygen environment on mesenchymal stem cell expansion and chondrogenic differentiation

(2009) A. Krinner et al.   CELL PROLIFERATION

Mechanics and mechanobiology of mesenchymal stem cell-based engineered cartilage

(2009) Alice H. Huang et al.   JOURNAL OF BIOMECHANICS

Engineering of Large Cartilaginous Tissues Through the Use of Microchanneled Hydrogels and Rotational Culture

(2009) Conor T. Buckley et al.   TISSUE ENGINEERING PART A

Zonal Chondrocytes Seeded in a Layered Agarose Hydrogel Create Engineered Cartilage with Depth-Dependent Cellular and Mechanical Inhomogeneity

(2009) Kenneth W. Ng et al.   TISSUE ENGINEERING PART A

Dynamic Compression Stimulates Proteoglycan Synthesis by Mesenchymal Stem Cells in the Absence of Chondrogenic Cytokines

(2009) John D. Kisiday et al.   TISSUE ENGINEERING PART A

Cartilage Tissue Engineering: Towards a Biomaterial-Assisted Mesenchymal Stem Cell Therapy

(2009) Claire Vinatier et al.   Current Stem Cell Research & Therapy

Dynamic compression can inhibit chondrogenesis of mesenchymal stem cells

(2008) S.D. Thorpe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cartilage matrix changes in the developing epiphysis: Early events on the pathway to equine osteochondrosis?

(2008) M. Lecocq et al.   EQUINE VETERINARY JOURNAL

Dynamic loading of deformable porous media can induce active solute transport

(2008) Michael B. Albro et al.   JOURNAL OF BIOMECHANICS

Hypoxia promotes chondrogenesis in rat mesenchymal stem cells: A role for AKT and hypoxia‐inducible factor (HIF)‐1α

(2008) Manoj Kanichai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The effect of concentration, thermal history and cell seeding density on the initial mechanical properties of agarose hydrogels

(2008) Conor T. Buckley et al.   Journal of the Mechanical Behavior of Biomedical Materials