Celastrol Prevents Atherosclerosis via Inhibiting LOX-1 and Oxidative Stress

Atherogenic effects of TNF-α and IL-6 via up-regulation of scavenger receptors

(2012) Misato Hashizume et al.   CYTOKINE

NF-kB activity-dependent P-selectin involved in ox-LDL-induced foam cell formation in U937 cell

(2011) Yi Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Celastrol Attenuates Hypertension-Induced Inflammation and Oxidative Stress in Vascular Smooth Muscle Cells via Induction of Heme Oxygenase-1

(2010) X. Yu et al.   AMERICAN JOURNAL OF HYPERTENSION

Celastrol inhibits the growth of estrogen positive human breast cancer cells through modulation of estrogen receptor α

(2010) Soon Young Jang et al.   CANCER LETTERS

Overexpression of scavenger receptor LOX-1 in endothelial cells promotes atherogenesis in the ApoE−/− mouse model

(2010) Stephen J. White et al.   CARDIOVASCULAR PATHOLOGY

SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

(2010) Sokrates Stein et al.   EUROPEAN HEART JOURNAL

Lipopolysaccharide up-regulates the expression of Fcα/μ receptor and promotes the binding of oxidized low-density lipoprotein and its IgM antibody complex to activated human macrophages

(2009) Xuyang Feng et al.   ATHEROSCLEROSIS

Palmitic acid enhances lectin-like oxidized LDL receptor (LOX-1) expression and promotes uptake of oxidized LDL in macrophage cells

(2009) Junichi Ishiyama et al.   ATHEROSCLEROSIS

Suppression of inflammatory responses by celastrol, a quinone methide triterpenoid isolated fromCelastrus regelii

(2009) D. H. Kim et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Effect of apocynin on NADPH oxidase-mediated oxidative stress-LOX-1-eNOS pathway in human endothelial cells exposed to high glucose

(2009) Ashraf Taye et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Role of Hydrogen Sulfide in the Development of Atherosclerotic Lesions in Apolipoprotein E Knockout Mice

(2008) Yanfei Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Celastrol inhibits the growth of human glioma xenografts in nude mice through suppressing VEGFR expression

(2008) Yulun Huang et al.   CANCER LETTERS