GAS6 Receptor Status Is Associated with Dormancy and Bone Metastatic Tumor Formation

An In Vivo Mouse Model for Human Prostate Cancer Metastasis

(2015) Aaron M. Havens et al.   NEOPLASIA

GAS6/AXL Axis Regulates Prostate Cancer Invasion, Proliferation, and Survival in the Bone Marrow Niche

(2015) Yusuke Shiozawa et al.   NEOPLASIA

Prevalence of Prostate Cancer Metastases after Intravenous Inoculation Provides Clues into the Molecular Basis of Dormancy in the Bone Marrow Microenvironment

(2015) Younghun Jung et al.   NEOPLASIA

Ecological Therapy for Cancer: Defining Tumors Using an Ecosystem Paradigm Suggests New Opportunities for Novel Cancer Treatments

(2014) Kenneth J. Pienta et al.   Translational Oncology

Prostate Cancer and Parasitism of the Bone Hematopoietic Stem Cell Niche

(2012) Chunyan Yu et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Hypoxia Stabilizes GAS6/Axl Signaling in Metastatic Prostate Cancer

(2012) Anjali Mishra et al.   MOLECULAR CANCER RESEARCH

Galectin-3 is a new MerTK-specific eat-me signal

(2011) Nora B. Caberoy et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow

(2011) Yusuke Shiozawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Genomic and Proteomic Analysis of the Impact of Mitotic Quiescence on the Engraftment of Human CD34+ Cells

(2011) Brahmananda Reddy Chitteti et al.   PLoS One

Plasma concentrations of Gas6 and sAxl correlate with disease activity in systemic lupus erythematosus

(2011) C. Ekman et al.   RHEUMATOLOGY

Design, Synthesis, and Biological Evaluation of a Series of Novel AXL Kinase Inhibitors

(2011) Alexis Mollard et al.   ACS Medicinal Chemistry Letters

Overexpression of receptor tyrosine kinase Axl promotes tumor cell invasion and survival in pancreatic ductal adenocarcinoma

(2010) Xianzhou Song et al.   CANCER

The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target

(2010) Jan-Bart M. Koorstra et al.   CANCER BIOLOGY & THERAPY

AXL Is an Essential Factor and Therapeutic Target for Metastatic Ovarian Cancer

(2010) E. B. Rankin et al.   CANCER RESEARCH

Plasma concentrations of Gas6 and soluble Axl correlate with disease and predict mortality in patients with critical limb ischemia

(2010) Carl Ekman et al.   CLINICAL BIOCHEMISTRY

Tubby and tubby-like protein 1 are new MerTK ligands for phagocytosis

(2010) Nora B Caberoy et al.   EMBO JOURNAL

Taking aim at Mer and Axl receptor tyrosine kinases as novel therapeutic targets in solid tumors

(2010) Rachel MA Linger et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Gas6 is complexed to the soluble tyrosine kinase receptor Axl in human blood

(2010) C. EKMAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

TAM receptor ligands in lupus: Protein S but not Gas6 levels reflect disease activity in systemic lupus erythematosus

(2010) Chang-Hee Suh et al.   ARTHRITIS RESEARCH & THERAPY

Up-Regulation of Soluble Axl and Mer Receptor Tyrosine Kinases Negatively Correlates with Gas6 in Established Multiple Sclerosis Lesions

(2009) Jason G. Weinger et al.   AMERICAN JOURNAL OF PATHOLOGY

Disseminated Tumor Cells in Prostate Cancer Patients after Radical Prostatectomy and without Evidence of Disease Predicts Biochemical Recurrence

(2009) T. M. Morgan et al.   CLINICAL CANCER RESEARCH

Awaking stem cells from dormancy: growing old and fighting cancer

(2009) Andrea Viale et al.   EMBO Molecular Medicine

Cancer micrometastasis and tumour dormancy 

(2008) HARRIET WIKMAN et al.   APMIS

Axl and Growth Arrest Specific Gene 6 Are Frequently Overexpressed in Human Gliomas and Predict Poor Prognosis in Patients with Glioblastoma Multiforme

(2008) M. Hutterer et al.   CLINICAL CANCER RESEARCH

Oncogenesis of T-ALL and nonmalignant consequences of overexpressing intracellular NOTCH1

(2008) Xiaoyu Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE