Poly-Ub-Substrate-Degradative Activity of 26S Proteasome Is Not Impaired in the Aging Rat Brain

Compensatory increase in USP14 activity accompanies impaired proteasomal proteolysis during aging

(2013) Subramaniam Ponnappan et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

(2012) Eva M. Huber et al.   CELL

Immunoproteasome in Cancer and Neuropathologies: A New Therapeutic Target?

(2012) Elena Bellavista et al.   CURRENT PHARMACEUTICAL DESIGN

Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

(2012) Cristina Pintado et al.   Journal of Neuroinflammation

Altered Composition of Liver Proteasome Assemblies Contributes to Enhanced Proteasome Activity in the Exceptionally Long-Lived Naked Mole-Rat

(2012) Karl A. Rodriguez et al.   PLoS One

Immunoproteasome expression is induced in mesial temporal lobe epilepsy

(2011) Michele Mishto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Impairment of Immunoproteasome Function by β5i/LMP7 Subunit Deficiency Results in Severe Enterovirus Myocarditis

(2011) Elisa Opitz et al.   PLoS Pathogens

Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

(2010) Ulrike Seifert et al.   CELL

Reduced Immunoproteasome Formation and Accumulation of Immunoproteasomal Precursors in the Brains of Lymphocytic Choriomeningitis Virus-Infected Mice

(2010) M. Kremer et al.   JOURNAL OF IMMUNOLOGY

The 26S proteasome: assembly and function of a destructive machine

(2010) Nerea Gallastegui et al.   TRENDS IN BIOCHEMICAL SCIENCES

Assembly, structure, and function of the 26S proteasome

(2010) Lynn Bedford et al.   TRENDS IN CELL BIOLOGY

Variably modulated gating of the 26S proteasome by ATP and polyubiquitin

(2009) Xiaohua Li et al.   BIOCHEMICAL JOURNAL

Aging and dietary restriction alter proteasome biogenesis and composition in the brain and liver

(2009) Kalavathi Dasuri et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Polyubiquitin substrates allosterically activate their own degradation by the 26S proteasome

(2009) Dawadschargal Bech-Otschir et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Aging Is Not Associated with Proteasome Impairment in UPS Reporter Mice

(2009) Casey Cook et al.   PLoS One

Heat shock and oxygen radicals stimulate ubiquitin-dependent degradation mainly of newly synthesized proteins

(2008) Balasubrahmanyam Medicherla et al.   JOURNAL OF CELL BIOLOGY

Age-related increase in the immunoproteasome content in rat hippocampus: molecular and functional aspects

(2008) M. Paz Gavilán et al.   JOURNAL OF NEUROCHEMISTRY

Genetic Evidence Linking Age-Dependent Attenuation of the 26S Proteasome with the Aging Process

(2008) A. Tonoki et al.   MOLECULAR AND CELLULAR BIOLOGY