Insulin Therapy for Pre-Hyperglycemic Beta-Cell Endoplasmic Reticulum Crowding

Basal Insulin and Cardiovascular and Other Outcomes in Dysglycemia

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

A Model of Threshold Behavior Reveals Rescue Mechanisms of Bystander Proteins in Conformational Diseases

(2011) Conner I. Sandefur et al.   BIOPHYSICAL JOURNAL

In Vivo Misfolding of Proinsulin Below the Threshold of Frank Diabetes

(2011) I. Hodish et al.   DIABETES

Pharmacokinetics and Pharmacodynamics of Basal Insulins

(2011) Francesca Porcellati et al.   Diabetes Technology & Therapeutics

Early insulin therapy prevents beta cell loss in a mouse model for permanent neonatal diabetes (Munich Ins2 C95S)

(2011) S. Kautz et al.   DIABETOLOGIA

Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic  -cells

(2011) M. Hatanaka et al.   HUMAN MOLECULAR GENETICS

The effort required to achieve and maintain optimal glycemic control

(2011) Elyse S. Rosenthal et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Insulin improves β-cell function in glucose-intolerant rat models induced by feeding a high-fat diet

(2011) Hui-qing Li et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Body Mass Index and Diabetes in Asia: A Cross-Sectional Pooled Analysis of 900,000 Individuals in the Asia Cohort Consortium

(2011) Paolo Boffetta et al.   PLoS One

PERK (EIF2AK3) Regulates Proinsulin Trafficking and Quality Control in the Secretory Pathway

(2010) Sounak Gupta et al.   DIABETES

Prevalence, Diagnosis, and Treatment of Impaired Fasting Glucose and Impaired Glucose Tolerance in Nondiabetic U.S. Adults

(2010) A. Karve et al.   DIABETES CARE

Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure

(2010) O. Kluth et al.   DIABETOLOGIA

Glucose regulation of islet stress responses and β-cell failure in type 2 diabetes

(2009) J. C. Jonas et al.   DIABETES OBESITY & METABOLISM

Pathomechanisms of Type 2 Diabetes Genes

(2009) Harald Staiger et al.   ENDOCRINE REVIEWS

Misfolded Proinsulin Affects Bystander Proinsulin in Neonatal Diabetes

(2009) Israel Hodish et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pdx1 (MODY4) regulates pancreatic beta cell susceptibility to ER stress

(2009) Mira M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Markers of glycemic control in the mouse: comparisons of 6-h- and overnight-fasted blood glucoses to Hb A1c

(2008) Byoung Geun Han et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Dilation of the endoplasmic reticulum in beta cells due to molecular overcrowding?

(2008) F. Despa   BIOPHYSICAL CHEMISTRY

Fasting Plasma C-Peptide and Micro- and Macrovascular Complications in a Large Clinic-Based Cohort of Type 1 Diabetic Patients

(2008) F. Panero et al.   DIABETES CARE

Beneficial Effects of Insulin on Glycemic Control and  -Cell Function in Newly Diagnosed Type 2 Diabetes With Severe Hyperglycemia After Short-Term Intensive Insulin Therapy

(2008) H.-S. Chen et al.   DIABETES CARE

Single-Nucleotide Polymorphism rs7754840 ofCDKAL1Is Associated with Impaired Insulin Secretion in Nondiabetic Offspring of Type 2 Diabetic Subjects and in a Large Sample of Men with Normal Glucose Tolerance

(2008) Alena Stančáková et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Effect of intensive insulin therapy on β-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial

(2008) Jianping Weng et al.   LANCET