Ginsenoside Rg1 Decreases Aβ1–42 Level by Upregulating PPARγ and IDE Expression in the Hippocampus of a Rat Model of Alzheimer's Disease

Ginsenoside Rg1 Attenuates Amyloid-β Content, Regulates PKA/CREB Activity, and Improves Cognitive Performance in SAMP8 Mice

(2017) Yan-Qing Shi et al.   JOURNAL OF ALZHEIMERS DISEASE

Insulin-Degrading Enzyme Sorting in Exosomes: A Secretory Pathway for a Key Brain Amyloid-β Degrading Protease

(2017) Ayelén Bulloj et al.   JOURNAL OF ALZHEIMERS DISEASE

In older patients, rosiglitazone was associated with increased risk for stroke, heart failure, and mortality compared with pioglitazone

(2013) Amy T. Wang et al.   ANNALS OF INTERNAL MEDICINE

Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model

(2011) Fang Fang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease

(2011) Jun Zhou et al.   BRAIN RESEARCH

Risk of Bladder Cancer Among Diabetic Patients Treated With Pioglitazone: Interim report of a longitudinal cohort study

(2011) J. D. Lewis et al.   DIABETES CARE

Telmisartan, a dual ARB/partial PPAR-γ agonist, protects myocardium from ischaemic reperfusion injury in experimental diabetes

(2011) S. N. Goyal et al.   DIABETES OBESITY & METABOLISM

Effect of pioglitazone on altered expression of Aβ metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance

(2011) Dingzhen Luo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ginsenoside Rg1 protects primary cultured rat hippocampal neurons from cell apoptosis induced by β-amyloid protein

(2011) Li Gong et al.   PHARMACEUTICAL BIOLOGY

Intramuscular delivery of a single chain antibody gene prevents brain Aβ deposition and cognitive impairment in a mouse model of Alzheimer’s disease

(2010) Yan-Jiang Wang et al.   BRAIN BEHAVIOR AND IMMUNITY

Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes

(2010) R. E. Aubert et al.   DIABETES OBESITY & METABOLISM

Genistein ameliorates learning and memory deficits in amyloid β(1–40) rat model of Alzheimer’s disease

(2010) Maryam Bagheri et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-κB activation

(2010) Qian Liu et al.   NEUROCHEMISTRY INTERNATIONAL

Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology

(2010) Luis Escribano et al.   NEUROPSYCHOPHARMACOLOGY

PPARγ transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons

(2009) Jing Du et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

(2009) R. Deane et al.   CNS & Neurological Disorders-Drug Targets

Insulin-Degrading Enzyme: Structure-Function Relationship and its Possible Roles in Health and Disease

(2009) A. Fernandez-Gamba et al.   CURRENT PHARMACEUTICAL DESIGN

Ginsenoside Rg1 inhibits β-secretase activityin vitroand protects against Aβ-induced cytotoxicity in PC12 cells

(2009) Yue-Hua Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Neprilysin and Insulin-Degrading Enzyme Levels Are Increased in Alzheimer Disease in Relation to Disease Severity

(2009) James Scott Miners et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

The study of ginsenoside on PPARγ expression of mononuclear macrophage in type 2 diabetes

(2009) Hai-xiang Ni et al.   MOLECULAR BIOLOGY REPORTS

Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease

(2008) Verónica Berta Dorfman et al.   NEUROBIOLOGY OF AGING

Increased expression of Aβ degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology

(2008) Saila Vepsäläinen et al.   NEUROSCIENCE LETTERS