Inhibition of P-Glycoprotein by HIV Protease Inhibitors Increases Intracellular Accumulation of Berberine in Murine and Human Macrophages

Lipid-lowering effect of berberine in human subjects and rats

(2012) Yueshan Hu et al.   PHYTOMEDICINE

A Novel Monocarbonyl Analogue of Curcumin, (1E,4E)-1,5-Bis(2,3-dimethoxyphenyl)penta-1,4-dien-3-one, Induced Cancer Cell H460 Apoptosis via Activation of Endoplasmic Reticulum Stress Signaling Pathway

(2011) Yi Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Activation of AMP-Activated Protein Kinase Is Required for Berberine-Induced Reduction of Atherosclerosis in Mice: The Role of Uncoupling Protein 2

(2011) Qilong Wang et al.   PLoS One

20(S)-Ginsenoside Rh2 Noncompetitively Inhibits P-Glycoprotein In Vitro and In Vivo: A Case for Herb-Drug Interactions

(2010) J. Zhang et al.   DRUG METABOLISM AND DISPOSITION

Extensive Intestinal First-Pass Elimination and Predominant Hepatic Distribution of Berberine Explain Its Low Plasma Levels in Rats

(2010) Y.-T. Liu et al.   DRUG METABOLISM AND DISPOSITION

Protease inhibitors atazanavir, lopinavir and ritonavir are potent blockers, but poor substrates, of ABC transporters in a broad panel of ABC transporter-overexpressing cell lines

(2010) W. F. W. Bierman et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

TNFα-induced and berberine-antagonized tight junction barrier impairment via tyrosine kinase, Akt and NFκB signaling

(2010) Maren Amasheh et al.   JOURNAL OF CELL SCIENCE

Development of a Novel Self-Microemulsifying Drug Delivery System for Reducing HIV Protease Inhibitor-Induced Intestinal Epithelial Barrier Dysfunction

(2010) Bokai Lei et al.   MOLECULAR PHARMACEUTICS

Berberine Inhibits HIV Protease Inhibitor-Induced Inflammatory Response by Modulating ER Stress Signaling Pathways in Murine Macrophages

(2010) Weibin Zha et al.   PLoS One

Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity

(2009) Woo Sik Kim et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Berberine suppresses proinflammatory responses through AMPK activation in macrophages

(2009) Hyun Woo Jeong et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

HIV protease inhibitor lopinavir-induced TNF-α and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages

(2009) Li Chen et al.   BIOCHEMICAL PHARMACOLOGY

P-Glycoprotein Mediates Efflux Transport of Darunavir in Human Intestinal Caco-2 and ABCB1 Gene-Transfected Renal LLC-PK1 Cell Lines

(2009) Hiromi Fujimoto et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Comparison of ABC Transporter Modulation by Atazanavir in Lymphocytes and Human Brain Endothelial Cells: ABC Transporters Are Involved in the Atazanavir-Limited Passage across an in Vitro Human Model of the Blood–Brain Barrier

(2008) Laurence Bousquet et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV therapy, metabolic syndrome, and cardiovascular risk

(2008) Vivian Pao et al.   Current Atherosclerosis Reports

Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

(2008) Jason A. Zastre et al.   JOURNAL OF NEUROSCIENCE RESEARCH