Interleukin-17 Expression Positively Correlates with Disease Severity of Lupus Nephritis by Increasing Anti-Double-Stranded DNA Antibody Production in a Lupus Model Induced by Activated Lymphocyte Derived DNA

Nasal Anti-CD3 Antibody Ameliorates Lupus by Inducing an IL-10-Secreting CD4+CD25-LAP+ Regulatory T Cell and Is Associated with Down-Regulation of IL-17+CD4+ICOS+CXCR5+ Follicular Helper T Cells

(2014) H. Y. Wu et al.   JOURNAL OF IMMUNOLOGY

Expanded Double Negative T Cells in Patients with Systemic Lupus Erythematosus Produce IL-17 and Infiltrate the Kidneys

(2014) J. C. Crispin et al.   JOURNAL OF IMMUNOLOGY

Production of anti-double-stranded DNA antibodies in activated lymphocyte derived DNA induced lupus model was dependent on CD4+ T cells

(2012) Z Wen et al.   LUPUS

The potential role of Th17 cells and Th17-related cytokines in the pathogenesis of lupus nephritis

(2012) D-Y Chen et al.   LUPUS

Recent advances in the IL-17 cytokine family

(2011) Sarah L Gaffen   CURRENT OPINION IN IMMUNOLOGY

Th Subset Balance in Lupus Nephritis

(2011) Katsuhisa Miyake et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Macrophage Differentiation and Polarization via Phosphatidylinositol 3-Kinase/Akt-ERK Signaling Pathway Conferred by Serum Amyloid P Component

(2011) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

IL-17-producing T cells in lupus nephritis

(2011) SA Apostolidis et al.   LUPUS

Amelioration of Lupus Nephritis by Serum Amyloid P Component Gene Therapy with Distinct Mechanisms Varied from Different Stage of the Disease

(2011) Weijuan Zhang et al.   PLoS One

Primary B-Cell Deficiencies Reveal a Link between Human IL-17-Producing CD4 T-Cell Homeostasis and B-Cell Differentiation

(2011) Rita R. Barbosa et al.   PLoS One

Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritis

(2011) Qian Xing et al.   RHEUMATOLOGY INTERNATIONAL

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

(2010) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Interleukin-17-producing T helper cells in autoimmunity

(2010) Nasr YA. Hemdan et al.   AUTOIMMUNITY REVIEWS

Plasma IL-17A Is Increased in New-Onset SLE Patients and Associated with Disease Activity

(2010) Xiao Qi Chen et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Blockade of Notch1 Signaling Alleviates Murine Lupus via Blunting Macrophage Activation and M2b Polarization

(2010) W. Zhang et al.   JOURNAL OF IMMUNOLOGY

A Small-Molecule Macrophage Migration Inhibitory Factor Antagonist Protects against Glomerulonephritis in Lupus-Prone NZB/NZW F1 and MRL/lpr Mice

(2010) L. Leng et al.   JOURNAL OF IMMUNOLOGY

Proinflammatory T helper type 17 cells are effective B-cell helpers

(2010) M. Mitsdoerffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Laser microdissection-based analysis of cytokine balance in the kidneys of patients with lupus nephritis

(2009) Y. Wang et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Interleukin 17 acts in synergy with B cell–activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus

(2009) Agnès Doreau et al.   NATURE IMMUNOLOGY

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells

(2009) Hee-Kap Kang et al.   ARTHRITIS RESEARCH & THERAPY

T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis

(2008) Robert A. Cohen et al.   CLINICAL IMMUNOLOGY

IL-17 and the Th17 lineage in systemic lupus erythematosus

(2008) Lee Ann Garrett-Sinha et al.   CURRENT OPINION IN RHEUMATOLOGY

Combined Deficiency of Proapoptotic Regulators Bim and Fas Results in the Early Onset of Systemic Autoimmunity

(2008) Jack Hutcheson et al.   IMMUNITY

Systemic Lupus Erythematosus

(2008) Anisur Rahman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Leukocytes and the kidney contribute to interstitial inflammation in lupus nephritis

(2007) L. Adalid-Peralta et al.   KIDNEY INTERNATIONAL