Temperature-Dependent Structural Changes of Parkinson's Alpha-Synuclein Reveal the Role of Pre-Existing Oligomers in Alpha-Synuclein Fibrillization
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Title
Temperature-Dependent Structural Changes of Parkinson's Alpha-Synuclein Reveal the Role of Pre-Existing Oligomers in Alpha-Synuclein Fibrillization
Authors
Keywords
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Journal
PLoS One
Volume 8, Issue 1, Pages e53487
Publisher
Public Library of Science (PLoS)
Online
2013-01-23
DOI
10.1371/journal.pone.0053487
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Note: Only part of the references are listed.- α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, andEscherichia coliExists Predominantly as Disordered Monomer
- (2012) Bruno Fauvet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2012) Q. Shu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Parkinson's Disease: Genetics and Pathogenesis
- (2011) Joshua M. Shulman et al. Annual Review of Pathology-Mechanisms of Disease
- The role of the C-terminus of human α-synuclein: Intra-disulfide bonds between the C-terminus and other regions stabilize non-fibrillar monomeric isomers
- (2011) Dong-Pyo Hong et al. FEBS LETTERS
- Distinct Effects of Zn2+, Cu2+, Fe3+, and Al3+on Amyloid-β Stability, Oligomerization, and Aggregation
- (2011) Wei-Ting Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
- (2011) Tim Bartels et al. NATURE
- A soluble -synuclein construct forms a dynamic tetramer
- (2011) W. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In vivo demonstration that -synuclein oligomers are toxic
- (2011) B. Winner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Conformation and the Aggregation Kinetics of α-Synuclein Depend on the Proline Residues in Its C-Terminal Region
- (2010) Jessika Meuvis et al. BIOCHEMISTRY
- Preparation and Characterization of Neurotoxic Tau Oligomers
- (2010) Cristian A. Lasagna-Reeves et al. BIOCHEMISTRY
- Molecular mechanism of Thioflavin-T binding to amyloid fibrils
- (2010) Matthew Biancalana et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- SDS-Induced Fibrillation of α-Synuclein: An Alternative Fibrillation Pathway
- (2010) Lise Giehm et al. JOURNAL OF MOLECULAR BIOLOGY
- Temperature-dependent structural changes in intrinsically disordered proteins: Formation of α-helices or loss of polyproline II?
- (2010) Magnus Kjaergaard et al. PROTEIN SCIENCE
- Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson’s Disease Revealed by Solution NMR Spectroscopy
- (2009) Christina R. Bodner et al. BIOCHEMISTRY
- Accelerated Fibrillation of α-Synuclein Induced by the Combined Action of Macromolecular Crowding and Factors Inducing Partial Folding
- (2009) L. Munishkina et al. Current Alzheimer Research
- Pre-fibrillar α-synuclein variants with impaired β-structure increase neurotoxicity in Parkinson's disease models
- (2009) Damla Pinar Karpinar et al. EMBO JOURNAL
- Exogenous -synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells
- (2009) K. C. Luk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dissociation of Amyloid Fibrils of α-Synuclein in Supercooled Water
- (2008) Hai-Young Kim et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Amyloid β-Protein Assembly and Alzheimer Disease
- (2008) Robin Roychaudhuri et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation at Ser-129 but Not the Phosphomimics S129E/D Inhibits the Fibrillation of α-Synuclein
- (2008) Katerina E. Paleologou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Characterization of Conformational and Dynamic Properties of Natively Unfolded Human and Mouse α-Synuclein Ensembles by NMR: Implication for Aggregation
- (2008) Kuen-Phon Wu et al. JOURNAL OF MOLECULAR BIOLOGY
- α-Synuclein Selectively Binds to Anionic Phospholipids Embedded in Liquid-Disordered Domains
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