The Protective Effect of Glycyrrhetinic Acid on Carbon Tetrachloride-Induced Chronic Liver Fibrosis in Mice via Upregulation of Nrf2

Superoxide dismutase 3 is induced by antioxidants, inhibits oxidative DNA damage and is associated with inhibition of estrogen-induced breast cancer

(2012) Bhupendra Singh et al.   CARCINOGENESIS

Iron overload and HFE gene mutations in Polish patients with liver cirrhosis

(2012) Katarzyna Sikorska et al.   Hepatobiliary & Pancreatic Diseases International

Nrf2 activation prevents cadmium-induced acute liver injury

(2012) Kai C. Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative stress and redox signaling mechanisms of alcoholic liver disease: Updated experimental and clinical evidence

(2011) Hong ZHU et al.   Journal of Digestive Diseases

Hepatitis C Virus Proteins Activate NRF2/ARE Pathway by Distinct ROS-Dependent and Independent Mechanisms in HUH7 Cells

(2011) Alexander V. Ivanov et al.   PLoS One

The role of Nrf2 signaling in the regulation of antioxidants and detoxifying enzymes after traumatic brain injury in rats and mice

(2010) Yuan Hong et al.   ACTA PHARMACOLOGICA SINICA

Proteasome inhibitor up regulates liver antioxidative enzymes in rat model of alcoholic liver disease

(2010) Fawzia Bardag-Gorce et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Effects of blueberry on hepatic fibrosis and transcription factorNrf2in rats

(2010) Yu-Ping Wang   WORLD JOURNAL OF GASTROENTEROLOGY

Role of oxidative stress in alcohol-induced liver injury

(2009) Arthur I. Cederbaum et al.   ARCHIVES OF TOXICOLOGY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Nrf2 Activation in Livers from Keap1-Knockdown Mice Increases Expression of Cytoprotective Genes that Detoxify Electrophiles more than those that Detoxify Reactive Oxygen Species

(2009) Scott A. Reisman et al.   TOXICOLOGICAL SCIENCES

Inhibition of liver fibrosis by solubilized coenzyme Q10: Role of Nrf2 activation in inhibiting transforming growth factor-β1 expression

(2009) Hoo-Kyun Choi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nrf2 protects against As(III)-induced damage in mouse liver and bladder

(2009) Tao Jiang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Down-Regulation of a Hepatic Transporter Multidrug Resistance-Associated Protein 2 Is Involved in Alteration of Pharmacokinetics of Glycyrrhizin and Its Metabolites in a Rat Model of Chronic Liver Injury

(2008) T. Makino et al.   DRUG METABOLISM AND DISPOSITION

Inhibitory effects of methanol extract of plum (Prunus salicina L., cv. ‘Soldam’) fruits against benzo(α)pyrene-induced toxicity in mice

(2008) Hyun Jeong Kim et al.   FOOD AND CHEMICAL TOXICOLOGY

Polymeric black tea polyphenols induce phase II enzymes via Nrf2 in mouse liver and lungs

(2008) Rachana Patel et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis

(2008) Weihua Xu et al.   LABORATORY INVESTIGATION

Glycyrrhizin and its metabolite inhibit Smad3-mediated type I collagen gene transcription and suppress experimental murine liver fibrosis

(2008) Tadashi Moro et al.   LIFE SCIENCES

Curcumin attenuates dimethylnitrosamine-induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1

(2007) E. Olatunde Farombi et al.   FOOD AND CHEMICAL TOXICOLOGY

Protective effects of Pycnogenol® on carbon tetrachloride-induced hepatotoxicity in Sprague–Dawley rats

(2007) Young-Su Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

The Nrf2–Keap1 defence pathway: Role in protection against drug-induced toxicity

(2007) Ian M. Copple et al.   TOXICOLOGY