pH-Responsive Artemisinin Derivatives and Lipid Nanoparticle Formulations Inhibit Growth of Breast Cancer Cells In Vitro and Induce Down-Regulation of HER Family Members

Interruption of the MEK/ERK signaling cascade promotes dihydroartemisinin-induced apoptosis in vitro and in vivo

(2011) Ning Gao et al.   APOPTOSIS

Resistance to HER2-directed antibodies and tyrosine kinase inhibitors

(2011) Joan T. Garrett et al.   CANCER BIOLOGY & THERAPY

ErbB3 Ablation Impairs PI3K/Akt-Dependent Mammary Tumorigenesis

(2011) R. S. Cook et al.   CANCER RESEARCH

Artemisinin: Discovery from the Chinese Herbal Garden

(2011) Louis H. Miller et al.   CELL

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Examining the role of cyclin D1 in breast cancer

(2011) Marco A Velasco-Velázquez et al.   Future Oncology

Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration

(2011) Carrie A Morris et al.   MALARIA JOURNAL

Anti-tumor effects of dihydroartemisinin on human osteosarcoma

(2011) Ye Ji et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Imaging the extracellular pH of tumors by MRI after injection of a single cocktail ofT1andT2contrast agents

(2011) Gary V. Martinez et al.   NMR IN BIOMEDICINE

Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

(2011) J. T. Garrett et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heme as Trigger and Target for Trioxane-Containing Antimalarial Drugs†

(2010) Bernard Meunier et al.   ACCOUNTS OF CHEMICAL RESEARCH

Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells

(2010) Colm Morrissey et al.   ANTI-CANCER DRUGS

In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents

(2010) Andrew M. Gravett et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Characteristics of triple-negative breast cancer

(2010) Tim C. de Ruijter et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Artesunate versus quinine in the treatment of severe falciparum malaria in African children (AQUAMAT): an open-label, randomised trial

(2010) Arjen M Dondorp et al.   LANCET

Artemisinin inhibits in vitro and in vivo invasion and metastasis of human hepatocellular carcinoma cells

(2010) Tan Weifeng et al.   PHYTOMEDICINE

The role of HER3, the unpretentious member of the HER family, in cancer biology and cancer therapeutics

(2010) Dhara N. Amin et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Cyclin D1 Degradation Is Sufficient to Induce G1 Cell Cycle Arrest despite Constitutive Expression of Cyclin E2 in Ovarian Cancer Cells

(2009) C. P. Masamha et al.   CANCER RESEARCH

Artemisinin and its derivatives: a novel class of anti-malarial and anti-cancer agents

(2009) Devdutt Chaturvedi et al.   CHEMICAL SOCIETY REVIEWS

Anticancer activities of artemisinin and its bioactive derivatives

(2009) Gary L. Firestone et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Artemisinin dimer anticancer activity correlates with heme-catalyzed reactive oxygen species generation and endoplasmic reticulum stress induction

(2009) Luke H. Stockwin et al.   INTERNATIONAL JOURNAL OF CANCER

Design, Synthesis and Antiproliferative Activities of Artemisinin Derivatives Containing a Substituted Piperazine

(2009) Xue-Lin Yang et al.   Letters in Drug Design & Discovery

Suppression of Cancer Cell Growth by Promoting Cyclin D1 Degradation

(2009) Jing Shan et al.   MOLECULAR CELL

Synthesis and evaluation of dihydroartemisinin and dihydroartemisitene acetal dimers showing anticancer and antiprotozoal activity

(2008) Ahmed M. Galal et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Transferrin receptor-dependent cytotoxicity of artemisinin–transferrin conjugates on prostate cancer cells and induction of apoptosis

(2008) Ikuhiko Nakase et al.   CANCER LETTERS

Cancer cells survive with survivin

(2008) Hirofumi Yamamoto et al.   CANCER SCIENCE

Interplay Between Malaria, Crystalline Hemozoin Formation, and Antimalarial Drug Action and Design

(2008) Isabelle Weissbuch et al.   CHEMICAL REVIEWS

Phase I and Pharmacokinetic Study of YM155, a Small-Molecule Inhibitor of Survivin

(2008) Anthony W. Tolcher et al.   JOURNAL OF CLINICAL ONCOLOGY

Qinghaosu (Artemisinin): The Price of Success

(2008) N. J. White   SCIENCE

pH-Dependent Interactions of Indinavir and Lipids in Nanoparticles and Their Ability to Entrap a Solute

(2007) Sung-Up Choi et al.   JOURNAL OF PHARMACEUTICAL SCIENCES