Deletion of 12/15-Lipoxygenase Alters Macrophage and Islet Function in NOD-Alox15null Mice, Leading to Protection against Type 1 Diabetes Development

12/15-Lipoxygenase Regulates the Inflammatory Response to Bacterial Products In Vivo

(2014) V. Dioszeghy et al.   JOURNAL OF IMMUNOLOGY

12/15-Lipoxygenase signaling in the endoplasmic reticulum stress response

(2012) Banumathi K. Cole et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Transcription Factor T-bet Is Induced by Multiple Pathways and Prevents an Endogenous Th2 Cell Program during Th1 Cell Responses

(2012) Jinfang Zhu et al.   IMMUNITY

Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunction

(2012) Jessica R. Weaver et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TLR4-mediated IL-12 production enhances IFN-γ and IL-1β production, which inhibits TGF-β production and promotes antibody-induced joint inflammation

(2012) Hye Kim et al.   ARTHRITIS RESEARCH & THERAPY

Progressive Erosion of  -Cell Function Precedes the Onset of Hyperglycemia in the NOD Mouse Model of Type 1 Diabetes

(2011) D. Ize-Ludlow et al.   DIABETES

Reducing or increasing β-cell apoptosis without inflammation does not affect diabetes initiation in neonatal NOD mice

(2011) Emma M. Carrington et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mitochondrial uncoupling protein 2 structure determined by NMR molecular fragment searching

(2011) Marcelo J. Berardi et al.   NATURE

Evidence for activation of inflammatory lipoxygenase pathways in visceral adipose tissue of obese Zucker rats

(2010) Swarup K. Chakrabarti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Prevention, but not cure, of autoimmune diabetes in a NOD.scidtransfer model by FTY720 despite effective modulation of blood T cells

(2010) Margaret A. Morris et al.   AUTOIMMUNITY

Etiology of Type 1 Diabetes

(2010) John A. Todd   IMMUNITY

Prediction and Pathogenesis in Type 1 Diabetes

(2010) Anette-G. Ziegler et al.   IMMUNITY

12-Lipoxygenase Products Reduce Insulin Secretion and β-Cell Viability in Human Islets

(2010) K. Ma et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice

(2010) Bernhard Maier et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional and pathological roles of the 12- and 15-lipoxygenases

(2010) Anca D. Dobrian et al.   PROGRESS IN LIPID RESEARCH

High sensitivity of β-cell replication to the inhibitory effects of interleukin-1β: modulation by adenoviral overexpression of IGF2 in rat islets

(2009) Elisabet Estil.les et al.   JOURNAL OF ENDOCRINOLOGY

  Cell-Specific CD4+ T Cell Clonotypes in Peripheral Blood and the Pancreatic Islets Are Distinct

(2009) L. Li et al.   JOURNAL OF IMMUNOLOGY

12/15-Lipoxygenase Products Induce Inflammation and Impair Insulin Signaling in 3T3-L1 Adipocytes

(2009) Swarup K. Chakrabarti et al.   Obesity

Role of 12/15-lipoxygenase in the expression of MCP-1 in mouse macrophages

(2008) Yeshao Wen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY