Instability of CTG Repeats is Governed by the Position of a DNA Base Lesion through Base Excision Repair

The Nucleotide Sequence, DNA Damage Location, and Protein Stoichiometry Influence the Base Excision Repair Outcome at CAG/CTG Repeats

(2012) Agathi-Vasiliki Goula et al.   BIOCHEMISTRY

Trinucleotide repeat deletion via a unique hairpin bypass by DNA polymerase β and alternate flap cleavage by flap endonuclease 1

(2012) Meng Xu et al.   NUCLEIC ACIDS RESEARCH

DNA base excision repair: a mechanism of trinucleotide repeat expansion

(2012) Yuan Liu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Trinucleotide Repeat DNA Alters Structure To Minimize the Thermodynamic Impact of 8-Oxo-7,8-dihydroguanine

(2011) Catherine B. Volle et al.   BIOCHEMISTRY

Incidence and persistence of 8-oxo-7,8-dihydroguanine within a hairpin intermediate exacerbates a toxic oxidation cycle associated with trinucleotide repeat expansion

(2011) Daniel A. Jarem et al.   DNA REPAIR

Base excision repair and design of small molecule inhibitors of human DNA polymerase β

(2010) Samuel H. Wilson et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bidirectional transcription stimulates expansion and contraction of expanded (CTG)•(CAG) repeats

(2010) Masayuki Nakamori et al.   HUMAN MOLECULAR GENETICS

Complementary Roles for Exonuclease 1 and Flap Endonuclease 1 in Maintenance of Triplet Repeats

(2010) Aarthy C. Vallur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of trinucleotide repeat instability during human development

(2010) Cynthia T. McMurray   NATURE REVIEWS GENETICS

Repeat instability as the basis for human diseases and as a potential target for therapy

(2010) Arturo López Castel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

DNA Polymerases β and λ Mediate Overlapping and Independent Roles in Base Excision Repair in Mouse Embryonic Fibroblasts

(2010) Elena K. Braithwaite et al.   PLoS One

Isolated short CTG/CAG DNA slip-outs are repaired efficiently by hMutSβ, but clustered slip-outs are poorly repaired

(2010) Gagan B. Panigrahi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Dependent DNA Damage and Repair in a Trinucleotide Repeat Sequence

(2009) Daniel A. Jarem et al.   BIOCHEMISTRY

Coordination between Polymerase β and FEN1 Can Modulate CAG Repeat Expansion

(2009) Yuan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stoichiometry of Base Excision Repair Proteins Correlates with Increased Somatic CAG Instability in Striatum over Cerebellum in Huntington's Disease Transgenic Mice

(2009) Agathi-Vassiliki Goula et al.   PLoS Genetics