Altered Processing of Amyloid Precursor Protein in Cells Undergoing Apoptosis

Development of a high-throughput screen targeting caspase-8-mediated cleavage of the amyloid precursor protein

(2011) Matthew J. Hart et al.   ANALYTICAL BIOCHEMISTRY

Mitosis-specific phosphorylation of amyloid precursor protein at Threonine 668 leads to its altered processing and association with centrosomes

(2011) Monique Judge et al.   Molecular Neurodegeneration

Chronic Intranasal Treatment with an Anti-Aβ30-42 scFv Antibody Ameliorates Amyloid Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) Susann Cattepoel et al.   PLoS One

Poly(ADP-ribose) polymerase signaling of topoisomerase 1-dependent DNA damage in carcinoma cells

(2010) Giovanna D’Onofrio et al.   BIOCHEMICAL PHARMACOLOGY

Caspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomes

(2010) Bärbel Edelmann et al.   EMBO JOURNAL

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

(2010) Marcello D'Amelio et al.   NATURE NEUROSCIENCE

Neuronal caspase-3 signaling: not only cell death

(2009) M D'Amelio et al.   CELL DEATH AND DIFFERENTIATION

Picomolar Amyloid-  Positively Modulates Synaptic Plasticity and Memory in Hippocampus

(2009) D. Puzzo et al.   JOURNAL OF NEUROSCIENCE

Identification of Novel APP/Aβ Isoforms in Human Cerebrospinal Fluid

(2009) Erik Portelius et al.   Neurodegenerative Diseases

Co-Localization of Amyloid Beta and Tau Pathology in Alzheimer's Disease Synaptosomes

(2008) Jeffrey A. Fein et al.   AMERICAN JOURNAL OF PATHOLOGY

The tumour suppressor p53 regulates the expression of amyloid precursor protein (APP)

(2008) Ascensión Cuesta et al.   BIOCHEMICAL JOURNAL

Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes

(2008) Mohamed Lamkanfi et al.   MOLECULAR & CELLULAR PROTEOMICS

Signal transduction in Alzheimer disease: p21-activated kinase signaling requires C-terminal cleavage of APP at Asp664

(2007) Thuy-Vi V. Nguyen et al.   JOURNAL OF NEUROCHEMISTRY