Primary Microcephaly Gene MCPH1 Shows Signatures of Tumor Suppressors and Is Regulated by miR-27a in Oral Squamous Cell Carcinoma

A Truncating Mutation of CEP135 Causes Primary Microcephaly and Disturbed Centrosomal Function

(2012) Muhammad Sajid Hussain et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BRIT1/MCPH1 is a multifunctional DNA damage responsive protein mediating DNA repair-associated chromatin remodeling

(2011) Guang Peng et al.   CELL CYCLE

Mutations in WDR62, encoding a centrosomal and nuclear protein, in Indian primary microcephaly families with cortical malformations

(2011) V Bhat et al.   CLINICAL GENETICS

Identification and functional characterization of a primate-specific E2F1 binding motif regulating MCPH1 expression

(2011) Lei Shi et al.   FEBS Journal

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway

(2011) Ralph Gruber et al.   NATURE CELL BIOLOGY

Craniosynostosis-microcephaly with chromosomal breakage and other abnormalities is caused by a truncating MCPH1 mutation and is allelic to premature chromosomal condensation syndrome and primary autosomal recessive microcephaly type 1

(2010) Muhammad Farooq et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Microcephalin is a new novel prognostic indicator in breast cancer associated with BRCA1 inactivation

(2010) Julie Richardson et al.   BREAST CANCER RESEARCH AND TREATMENT

ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target

(2010) Sandra-Nadia Bikeye et al.   Cancer Cell International

miR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2

(2010) Yihui Ma et al.   CANCER LETTERS

The Origins and Implications of Intratumor Heterogeneity

(2010) F. Michor et al.   Cancer Prevention Research

Differential regulation of centrosome integrity by DNA damage response proteins

(2010) Rekha Rai et al.   CELL CYCLE

Mechanisms of Inactivation of PTCH1 Gene in Nevoid Basal Cell Carcinoma Syndrome: Modification of the Two-Hit Hypothesis

(2010) S. Pan et al.   CLINICAL CANCER RESEARCH

Comprehensive MicroRNA Profiling for Head and Neck Squamous Cell Carcinomas

(2010) A. B.Y. Hui et al.   CLINICAL CANCER RESEARCH

Double strand break repair components are frequent targets of microsatellite instability in endometrial cancer

(2010) Cristina Bilbao et al.   EUROPEAN JOURNAL OF CANCER

A clinical and molecular genetic study of 112 Iranian families with primary microcephaly

(2010) H. Darvish et al.   JOURNAL OF MEDICAL GENETICS

CEP152 is a genome maintenance protein disrupted in Seckel syndrome

(2010) Ersan Kalay et al.   NATURE GENETICS

MCPH1/BRIT1 limits ionizing radiation-induced centrosome amplification

(2010) J A L Brown et al.   ONCOGENE

Establishment of a Mouse Model with Misregulated Chromosome Condensation due to Defective Mcph1 Function

(2010) Marc Trimborn et al.   PLoS One

BRIT1/MCPH1 Is Essential for Mitotic and Meiotic Recombination DNA Repair and Maintaining Genomic Stability in Mice

(2010) Yulong Liang et al.   PLoS Genetics

Mutations in STIL, Encoding a Pericentriolar and Centrosomal Protein, Cause Primary Microcephaly

(2009) Arun Kumar et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Cell line cross-contamination: KB is not an oral squamous cell carcinoma cell line

(2009) Lu Jiang et al.   EUROPEAN JOURNAL OF ORAL SCIENCES

Microcephalin and pericentrin regulate mitotic entry via centrosome-associated Chk1

(2009) Alexandra Tibelius et al.   JOURNAL OF CELL BIOLOGY

Many roads lead to primary autosomal recessive microcephaly

(2009) Angela M. Kaindl et al.   PROGRESS IN NEUROBIOLOGY

Involvement of TSC genes and differential expression of other members of the mTOR signaling pathway in oral squamous cell carcinoma

(2008) Sanjukta Chakraborty et al.   BMC CANCER

miR-Q: a novel quantitative RT-PCR approach for the expression profiling of small RNA molecules such as miRNAs in a complex sample

(2008) Soroush Sharbati-Tehrani et al.   BMC MOLECULAR BIOLOGY

MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis

(2008) Shan-Zhong Yang et al.   EMBO REPORTS

Promoter characterization and regulation of expression of an imprinted gene SLC22A18AS

(2008) Vineeta Bajaj et al.   GENE

Microcephalin/MCPH1 Associates with the Condensin II Complex to Function in Homologous Recombination Repair

(2008) Jamie L. Wood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of caspase-3 and caspase-8 deregulation in tongue squamous cell carcinoma, based on immunohistochemistry and computerised image analysis

(2008) D Andressakis et al.   JOURNAL OF LARYNGOLOGY AND OTOLOGY