Nexilin, a Cardiomyopathy-Associated F-Actin Binding Protein, Binds and Regulates IRS1 Signaling in Skeletal Muscle Cells

GLUT4 exocytosis

(2012) Jacqueline Stöckli et al.   JOURNAL OF CELL SCIENCE

Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle

(2011) Tim T. Chiu et al.   CELLULAR SIGNALLING

Phosphoinositide 3-Kinase (PI3K(p110α)) Directly Regulates Key Components of the Z-disc and Cardiac Structure

(2011) Ashley J. Waardenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cardiac Z-disc Signaling Network

(2011) Derk Frank et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling, cytoskeletal and membrane mechanisms regulating GLUT4 exocytosis

(2011) Nolan J. Hoffman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mutations in NEXN, a Z-Disc Gene, Are Associated with Hypertrophic Cardiomyopathy

(2010) Hu Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents

(2010) Ippei Shimizu et al.   JOURNAL OF CLINICAL INVESTIGATION

Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy

(2009) David Hassel et al.   NATURE MEDICINE