An Inverse Switch in DNA Base Excision and Strand Break Repair Contributes to Melphalan Resistance in Multiple Myeloma Cells

Differential effects of poly(ADP-ribose) polymerase inhibition on DNA break repair in human cells are revealed with Epstein-Barr virus

(2012) W. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro primary human lymphocyte flow cytometry based micronucleus assay: simultaneous assessment of cell proliferation, apoptosis and MN frequency

(2011) M. Lukamowicz et al.   MUTAGENESIS

Induction and repair of DNA double strand breaks: The increasing spectrum of non-homologous end joining pathways

(2011) Emil Mladenov et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

c-MYC Suppresses BIN1 to Release Poly(ADP-Ribose) Polymerase 1: A Mechanism by Which Cancer Cells Acquire Cisplatin Resistance

(2011) S. Pyndiah et al.   Science Signaling

Thalidomide versus bortezomib based regimens as first-line therapy for patients with multiple myeloma: A systematic review

(2010) Ambuj Kumar et al.   AMERICAN JOURNAL OF HEMATOLOGY

Recognition of Platinum−DNA Damage by Poly(ADP-ribose) Polymerase-1

(2010) Guangyu Zhu et al.   BIOCHEMISTRY

Drugging Drug Resistance

(2010) Jan-Hermen Dannenberg et al.   CELL

Tumor Suppressor CHK2: Regulator of DNA Damage Response and Mediator of Chromosomal Stability

(2010) A. Stolz et al.   CLINICAL CANCER RESEARCH

The Fanconi anemia pathway and ICL repair: implications for cancer therapy

(2010) Lily C Wang et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cell cycle arrest and DNA damage after melphalan treatment of the human myeloma cell line RPMI 8226

(2010) Jan-Olof Fernberg et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

A novel link to base excision repair?

(2010) David M. Wilson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mechanisms of double-strand break repair in somatic mammalian cells

(2009) Andrea J. Hartlerode et al.   BIOCHEMICAL JOURNAL

Targeting the Fanconi Anemia/BRCA Pathway Circumvents Drug Resistance in Multiple Myeloma

(2009) D. N. Yarde et al.   CANCER RESEARCH

Emerging common themes in regulation of PIKKs and PI3Ks

(2009) Harri Lempiäinen et al.   EMBO JOURNAL

The Human Oxidative DNA Glycosylase NEIL1 Excises Psoralen-induced Interstrand DNA Cross-links in a Three-stranded DNA Structure

(2009) Sophie Couvé et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple myeloma

(2009) Marc S Raab et al.   LANCET

APE1 overexpression is associated with cisplatin resistance in non-small cell lung cancer and targeted inhibition of APE1 enhances the activity of cisplatin in A549 cells

(2009) Dong Wang et al.   LUNG CANCER

Histone H2AX phosphorylation as a molecular pharmacological marker for DNA interstrand crosslink cancer chemotherapy

(2008) P.H. Clingen et al.   BIOCHEMICAL PHARMACOLOGY

Multiple myeloma

(2008) R. A. Kyle et al.   BLOOD

Treatment of newly diagnosed myeloma

(2008) A Palumbo et al.   LEUKEMIA

δ-Aminolevulinate dehydratase activity and oxidative stress during melphalan and cyclophosphamide–BCNU–etoposide (CBV) conditioning regimens in autologous bone marrow transplantation patients

(2008) Thissiane L. Gonçalves et al.   PHARMACOLOGICAL RESEARCH

Effect of double-strand break DNA sequence on the PARP-1 NHEJ pathway

(2007) Marc Audebert et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS