Global DNA Hypomethylation Prevents Consolidation of Differentiation Programs and Allows Reversion to the Embryonic Stem Cell State

Role of DNMT3B in the regulation of early neural and neural crest specifiers

(2012) Kristen Martins-Taylor et al.   Epigenetics

Chromatin Connections to Pluripotency and Cellular Reprogramming

(2011) Stuart H. Orkin et al.   CELL

Pluripotency Factors in Embryonic Stem Cells Regulate Differentiation into Germ Layers

(2011) Matt Thomson et al.   CELL

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells

(2011) Derk ten Berge et al.   NATURE CELL BIOLOGY

The transcriptional and signalling networks of pluripotency

(2011) Huck-Hui Ng et al.   NATURE CELL BIOLOGY

DNA Methylation Profiling of Embryonic Stem Cell Differentiation into the Three Germ Layers

(2011) Takayuki Isagawa et al.   PLoS One

Differential Recruitment of Methyl CpG-Binding Domain Factors and DNA Methyltransferases by the Orphan Receptor Germ Cell Nuclear Factor Initiates the Repression and Silencing of Oct4

(2011) Peili Gu et al.   STEM CELLS

Nucleosomes Containing Methylated DNA Stabilize DNA Methyltransferases 3A/3B and Ensure Faithful Epigenetic Inheritance

(2011) Shikhar Sharma et al.   PLoS Genetics

BISMA - Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences

(2010) Christian Rohde et al.   BMC BIOINFORMATICS

A Myc Network Accounts for Similarities between Embryonic Stem and Cancer Cell Transcription Programs

(2010) Jonghwan Kim et al.   CELL

DNA Methylation Is Dispensable for the Growth and Survival of the Extraembryonic Lineages

(2010) Morito Sakaue et al.   CURRENT BIOLOGY

The origin and identity of embryonic stem cells

(2010) J. Nichols et al.   DEVELOPMENT

Polycomb complexes act redundantly to repress genomic repeats and genes

(2010) M. Leeb et al.   GENES & DEVELOPMENT

LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease

(2010) Dean S. Griffiths et al.   NATURE CELL BIOLOGY

Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA

(2010) Aleksandra Szwagierczak et al.   NUCLEIC ACIDS RESEARCH

Targeting of De Novo DNA Methylation Throughout the Oct-4 Gene Regulatory Region in Differentiating Embryonic Stem Cells

(2010) Rodoniki Athanasiadou et al.   PLoS One

Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes

(2010) H. Wu et al.   SCIENCE

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

(2009) Hitoshi Niwa et al.   NATURE

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

(2009) Jochen Utikal et al.   NATURE

The Ink4/Arf locus is a barrier for iPS cell reprogramming

(2009) Han Li et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Neural Differentiation of Embryonic Stem Cells In Vitro: A Road Map to Neurogenesis in the Embryo

(2009) Elsa Abranches et al.   PLoS One

Capturing Pluripotency

(2008) Jose Silva et al.   CELL

Promoter CpG Methylation Contributes to ES Cell Gene Regulation in Parallel with Oct4/Nanog, PcG Complex, and Histone H3 K4/K27 Trimethylation

(2008) Shaun D. Fouse et al.   Cell Stem Cell

Induction of Pluripotent Stem Cells from Mouse Embryonic Fibroblasts by Oct4 and Klf4 with Small-Molecule Compounds

(2008) Yan Shi et al.   Cell Stem Cell

Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors

(2008) Fabio Mohn et al.   MOLECULAR CELL

Transient cyclical methylation of promoter DNA

(2008) Sara Kangaspeska et al.   NATURE

Dissecting direct reprogramming through integrative genomic analysis

(2008) Tarjei S. Mikkelsen et al.   NATURE

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5

(2008) Ray Kit Ng et al.   NATURE CELL BIOLOGY

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

(2008) Manching Ku et al.   PLoS Genetics