PARP-1 Modulation of mTOR Signaling in Response to a DNA Alkylating Agent

ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy

(2012) José Manuel Rodríguez-Vargas et al.   CELL RESEARCH

Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer

(2012) Ashish Juvekar et al.   Cancer Discovery

Oxidative stress initiates DNA damager MNNG-induced poly(ADP-ribose)polymerase-1-dependent parthanatos cell death

(2010) Ling-Ya Chiu et al.   BIOCHEMICAL PHARMACOLOGY

Poly (ADP-ribose) polymerase activity regulates apoptosis in HeLa cells after alkylating DNA damage

(2010) Xuesong Liu et al.   CANCER BIOLOGY & THERAPY

AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

(2010) L. Harhaji-Trajkovic et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rictor Phosphorylation on the Thr-1135 Site Does Not Require Mammalian Target of Rapamycin Complex 2

(2010) D. Boulbes et al.   MOLECULAR CANCER RESEARCH

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

(2009) R. J. Shaw   Acta Physiologica

PARP-1 is involved in autophagy induced by DNA damage

(2009) José Antonio Muñoz-Gámez et al.   Autophagy

A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1

(2009) Jingxiang Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells

(2009) Griselda Herrero-Martín et al.   EMBO JOURNAL

Parthanatos, a messenger of death

(2009) Karen Kate David   Frontiers in Bioscience-Landmark

The molecular "Jekyll and Hyde" duality of PARP1 in cell death and cell survival

(2009) Paul et al.   Frontiers in Bioscience-Landmark

Poly(ADP-ribose) Catabolism Triggers AMP-dependent Mitochondrial Energy Failure

(2009) Laura Formentini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MAPK, Phosphatidylinositol 3-Kinase, and Mammalian Target of Rapamycin Pathways Converge at the Level of Ribosomal Protein S6 Phosphorylation to Control Metabolic Signaling in CD8 T Cells

(2009) R. J. Salmond et al.   JOURNAL OF IMMUNOLOGY

Characterization of Rictor Phosphorylation Sites Reveals Direct Regulation of mTOR Complex 2 by S6K1

(2009) C. C. Dibble et al.   MOLECULAR AND CELLULAR BIOLOGY

mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling

(2009) L.-A. Julien et al.   MOLECULAR AND CELLULAR BIOLOGY

Rictor is a novel target of p70 S6 kinase-1

(2009) C Treins et al.   ONCOGENE

Somatic LKB1 Mutations Promote Cervical Cancer Progression

(2009) Shana N. Wingo et al.   PLoS One

The regulation of AMP-activated protein kinase by upstream kinases

(2008) D Carling et al.   INTERNATIONAL JOURNAL OF OBESITY

PKBα/Akt1 Acts Downstream of DNA-PK in the DNA Double-Strand Break Response and Promotes Survival

(2008) Lana Bozulic et al.   MOLECULAR CELL

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes

(2008) Jean-Philippe Gagné et al.   NUCLEIC ACIDS RESEARCH

Regulation of macroautophagy by mTOR and Beclin 1 complexes

(2007) Sophie Pattingre et al.   BIOCHIMIE