4.6 Article

Inappropriate Fiddling with Statistical Analyses to Obtain a Desirable P-value: Tests to Detect its Presence in Published Literature

Journal

PLOS ONE
Volume 7, Issue 10, Pages -

Publisher

PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0046363

Keywords

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Funding

  1. Coca-Cola Company
  2. United States National Institutes of Health/NIDDK [P30DK056336]

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Much has been written regarding p-values below certain thresholds (most notably 0.05) denoting statistical significance and the tendency of such p-values to be more readily publishable in peer-reviewed journals. Intuition suggests that there may be a tendency to manipulate statistical analyses to push a near significant p-value'' to a level that is considered significant. This article presents a method for detecting the presence of such manipulation (herein called fiddling'') in a distribution of p-values from independent studies. Simulations are used to illustrate the properties of the method. The results suggest that the method has low type I error and that power approaches acceptable levels as the number of p-values being studied approaches 1000.

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