Effects of the CK2 Inhibitors CX-4945 and CX-5011 on Drug-Resistant Cells

ABC transporters and their role in nucleoside and nucleotide drug resistance

(2012) Yu Fukuda et al.   BIOCHEMICAL PHARMACOLOGY

Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells

(2012) Joshua Bliesath et al.   CANCER LETTERS

Protein Kinase CK2 Protects Multiple Myeloma Cells from ER Stress-Induced Apoptosis and from the Cytotoxic Effect of HSP90 Inhibition through Regulation of the Unfolded Protein Response

(2012) S. Manni et al.   CLINICAL CANCER RESEARCH

CK2 Inhibitor CX-4945 Suppresses DNA Repair Response Triggered by DNA-Targeted Anticancer Drugs and Augments Efficacy: Mechanistic Rationale for Drug Combination Therapy

(2012) A. Siddiqui-Jain et al.   MOLECULAR CANCER THERAPEUTICS

Acquired resistance to drugs targeting receptor tyrosine kinases

(2011) Steven A. Rosenzweig   BIOCHEMICAL PHARMACOLOGY

Unprecedented Selectivity and Structural Determinants of a New Class of Protein Kinase CK2 Inhibitors in Clinical Trials for the Treatment of Cancer

(2011) Roberto Battistutta et al.   BIOCHEMISTRY

ATP Site-Directed Inhibitors of Protein Kinase CK2: An Update

(2011) S. Sarno et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Protein kinase CK2 accumulation in “oncophilic” cells: causes and effects

(2011) Maria Ruzzene et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Emergence of protein kinase CK2 as a key target in cancer therapy

(2010) Janeen H. Trembley et al.   BIOFACTORS

Antitumor Activity of Pyridocarbazole and Benzopyridoindole Derivatives that Inhibit Protein Kinase CK2

(2010) R. Prudent et al.   CANCER RESEARCH

CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy

(2010) A. Siddiqui-Jain et al.   CANCER RESEARCH

Synergistic activity of the Src/Abl inhibitor bosutinib in combination with imatinib

(2010) S Redaelli et al.   LEUKEMIA

Extraordinary pleiotropy of protein kinase CK2 revealed by weblogo phosphoproteome analysis

(2009) Mauro Salvi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Addiction to protein kinase CK2: A common denominator of diverse cancer cells?

(2009) Maria Ruzzene et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Protein Kinase CK2 in Health and Disease

(2009) R. Battistutta   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase CK2 in Health and Disease

(2009) I. Dominguez et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase CK2 in Health and Disease

(2009) N. A. St-Denis et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protein Kinase CK2 in Health and Disease

(2009) J. H. Trembley et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Multidrug Resistance Through the Spectacle of P-Glycoprotein

(2009) Katalin Goda et al.   CURRENT CANCER DRUG TARGETS

Comparative analysis of CK2 expression and function in tumor cell lines displaying sensitivity vs. resistance to chemical induced apoptosis

(2008) Giovanni Di Maira et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Too much of a good thing: The role of protein kinase CK2 in tumorigenesis and prospects for therapeutic inhibition of CK2

(2007) James S. Duncan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS