TBK1 Kinase Addiction in Lung Cancer Cells Is Mediated via Autophagy of Tax1bp1/Ndp52 and Non-Canonical NF-κB Signalling

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

(2014) Daniel J. Klionsky et al.   Autophagy

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

(2012) Manohar Pilli et al.   IMMUNITY

Selective Autophagy of the Adaptor Protein Bcl10 Modulates T Cell Receptor Activation of NF-κB

(2012) Suman Paul et al.   IMMUNITY

LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy

(2012) Natalia von Muhlinen et al.   MOLECULAR CELL

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

(2012) Teresa L. M. Thurston et al.   NATURE

Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model

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Blocking Autophagy Prevents Bortezomib-Induced NF-κB Activation by Reducing I-κBα Degradation in Lymphoma Cells

(2012) Li Jia et al.   PLoS One

NSCLC and the alternative pathway of NF-κB: uncovering an unknown relation

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Viral Mediated Redirection of NEMO/IKKγ to Autophagosomes Curtails the Inflammatory Cascade

(2012) Patricia M. Fliss et al.   PLoS Pathogens

Pancreatic cancers require autophagy for tumor growth

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Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

Involvement of Autophagy in Oncogenic K-Ras-induced Malignant Cell Transformation

(2011) Min-Jung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagosomal IκBα Degradation Plays a Role in the Long Term Control of Tumor Necrosis Factor-α-induced Nuclear Factor-κB (NF-κB) Activity

(2011) Amy Colleran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncogenic Ras-Induced Expression of Noxa and Beclin-1 Promotes Autophagic Cell Death and Limits Clonogenic Survival

(2011) Mohamed Elgendy et al.   MOLECULAR CELL

TBK1 Directly Engages Akt/PKB Survival Signaling to Support Oncogenic Transformation

(2011) Yi-Hung Ou et al.   MOLECULAR CELL

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

(2011) Gen Matsumoto et al.   MOLECULAR CELL

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis

(2011) H Nikki March et al.   NATURE GENETICS

The TRAF-associated protein TANK facilitates cross-talk within the I B kinase family during Toll-like receptor signaling

(2011) K. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

I B kinase   and TANK-binding kinase 1 activate AKT by direct phosphorylation

(2011) X. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

(2011) P. Wild et al.   SCIENCE

Requirement of the NF-κB Subunit p65/RelA for K-Ras–Induced Lung Tumorigenesis

(2010) Daniela S. Bassères et al.   CANCER RESEARCH

Autophagy: an adaptable modifier of tumourigenesis

(2010) Simon Wilkinson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases

(2010) Kislay Parvatiyar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

(2010) Rebecca Lock et al.   MOLECULAR BIOLOGY OF THE CELL

RETRACTED: The Skp2 Promoter Integrates Signaling through the NF-κB, p53, and Akt/GSK3β Pathways to Regulate Autophagy and Apoptosis

(2010) Benjamin Barré et al.   MOLECULAR CELL

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Inhibition of NF- B Signaling by A20 Through Disruption of Ubiquitin Enzyme Complexes

(2010) N. Shembade et al.   SCIENCE

Autophagy Suppresses Tumorigenesis through Elimination of p62

(2009) Robin Mathew et al.   CELL

Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity

(2009) S. Wilkinson et al.   GENES & DEVELOPMENT

Autophagy mediates the mitotic senescence transition

(2009) A. R.J. Young et al.   GENES & DEVELOPMENT

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

(2009) David A. Barbie et al.   NATURE

Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma

(2009) Etienne Meylan et al.   NATURE

The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria

(2009) Teresa L M Thurston et al.   NATURE IMMUNOLOGY

NRP/Optineurin Cooperates with TAX1BP1 to Potentiate the Activation of NF-κB by Human T-Lymphotropic Virus Type 1 Tax Protein

(2009) Chloé Journo et al.   PLoS Pathogens

Inflammatory cardiac valvulitis in TAX1BP1-deficient mice through selective NF-κB activation

(2008) Hidekatsu Iha et al.   EMBO JOURNAL

Prolonged Classical NF-κB Activation Prevents Autophagy uponE. coliStimulation In Vitro: A Potential Resolving Mechanism of Inflammation

(2008) Silke Schlottmann et al.   MEDIATORS OF INFLAMMATION

Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?

(2008) Tieu-Lan Chau et al.   TRENDS IN BIOCHEMICAL SCIENCES