A Novel Interplay between Rap1 and PKA Regulates Induction of Angiogenesis in Prostate Cancer

Rap1b Regulates B Cell Development, Homing, and T Cell-Dependent Humoral Immunity

(2014) H. Chu et al.   JOURNAL OF IMMUNOLOGY

Rap1 promotes VEGFR2 activation and angiogenesis by a mechanism involving integrin  v 3

(2011) S. Lakshmikanthan et al.   BLOOD

Distinct Roles for Rap1b Protein in Platelet Secretion and Integrin αIIbβ3Outside-in Signaling

(2011) Guoying Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of GTPases in control of microvascular permeability

(2010) V. Spindler et al.   CARDIOVASCULAR RESEARCH

Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes

(2010) Aradhana Awasthi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PKA and Epac synergistically inhibit smooth muscle cell proliferation

(2010) Richard C. Hewer et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Regulation of angiogenesis by a small GTPase Rap1

(2010) Magdalena Chrzanowska-Wodnicka   VASCULAR PHARMACOLOGY

A novel interplay between Epac/Rap1 and mitogen-activated protein kinase kinase 5/extracellular signal-regulated kinase 5 (MEK5/ERK5) regulates thrombospondin to control angiogenesis

(2009) R. C. Doebele et al.   BLOOD

Epac inhibits migration and proliferation of human prostate carcinoma cells

(2009) M Grandoch et al.   BRITISH JOURNAL OF CANCER

Activation of Rap1 Promotes Prostate Cancer Metastasis

(2009) C. L. Bailey et al.   CANCER RESEARCH

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

(2009) Massimiliano Mazzone et al.   CELL

Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis

(2008) G. Carmona et al.   BLOOD

Rap1a Is a Key Regulator of Fibroblast Growth Factor 2-Induced Angiogenesis and Together with Rap1b Controls Human Endothelial Cell Functions

(2008) J. Yan et al.   MOLECULAR AND CELLULAR BIOLOGY

Epac-selective cAMP analogs: New tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors

(2007) George G. Holz et al.   CELLULAR SIGNALLING