Article
Green & Sustainable Science & Technology
Jean-Luc Kouassi, Allegra Kouassi, Yeboi Bene, Dieudonne Konan, Ebagnerin J. Tondoh, Christophe Kouame
Summary: Agroforestry is essential for sustainable cocoa production and addressing global challenges. The study found that a majority of farmers practicing full-sun cocoa farming are willing to plant and maintain companion trees for ecosystem services.
Article
Medicine, General & Internal
Maxime Inghels, Arsene Kra Kouassi, Serge Niangoran, Anne Bekelynck, Severine Carilon, Lazare Sika, Mariatou Kone, Christine Danel, Annabel Degrees du Lou, Joseph Larmarange
Summary: This study in Cote d'Ivoire aimed to measure access to and preferences for community-based HIV testing sites for men who have sex with men (MSM). The results showed that only half of the respondents knew about MSM-focused community-based HIV testing sites, and knowing and visiting such sites were associated with a higher number of HIV tests and disclosure of sexual orientation. Preferences for HIV testing sites varied, with some preferring undifferentiated sites and others preferring MSM-focused sites.
Article
Multidisciplinary Sciences
Nancy Mugisha, Fatoumata Tirera, Naraba Coulibaly-Kouyate, William Aguie, Yao He, Kathryn Kemper, Julia Robinson, Luc N'Goran, Moise Tuho, Seydou Kouyate, Yacouba Doumbia, Stephen Gloyd, Ahoua Kone
Summary: Index testing is a focused HIV testing service approach that investigates the implementation process and challenges in Cote d'Ivoire. Non-clinical providers are responsible for implementing index testing, and passive referral and providers referral are the preferred contact tracing and testing strategies. Challenges include a refusal to provide partner information, fear of divorce, societal stigma, long distances, lack of appropriate training, and lack of privacy. Recommendations include reinforcing HIV education, training healthcare workers, and improving infrastructure and resources.
Article
Health Care Sciences & Services
Kadidiatou Raissa Kourouma, Marie Laurette Agbre-Yace, Daouda Doukoure, Lassina Cisse, Chantiere Some-Meazieu, Joseph Ouattara, Akoua Tano-Kamelan, Virginie Konan Kouakou
Summary: The study identified barriers to the implementation of Kangaroo Mother Care (KMC) in Cote d'Ivoire, such as lack of supplies, insufficient human resources, and resistance from fathers. Facilitators included training of healthcare providers, strong leadership, and the low cost of KMC. Proposed solutions for improving KMC implementation included motivating volunteer staff, educating and counseling mothers and families, and involving all stakeholders in the process. Recommendations were made for researchers and decision makers to address these specific barriers to enhance the uptake of KMC.
BMC HEALTH SERVICES RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Arielle Lasry, Nathalie K. Danho, Erin N. Hulland, Annie D. Diokouri, Marie-Huguette Kingbo, Nicole I. L. Doumatey, Alexandre K. Ekra, Laurence G. Ebah, Hoba Kouame, Judith Hedje, Anne-Eudes Jean-Baptiste
Summary: The Family Approach to Counseling and Testing (FACT) program in Cote d'Ivoire, which provides HIV testing to the family members of HIV-positive index cases, has proven to be an effective approach to case finding. The program showed positivity rates of 21% among partners, 5% among children, and 11% among other family members. Offering HIV testing to partners of positive women index cases can be key to identifying undiagnosed men and linking them to treatment.
Article
Public, Environmental & Occupational Health
Marc d'Elbee, Metogara Mohamed Traore, Keba Badiane, Anthony Vautier, Arlette Simo Fotso, Ode Kanku Kabemba, Nicolas Rouveau, Peter Godfrey-Faussett, Mathieu Maheu-Giroux, Marie-Claude Boily, Graham Francis Medley, Joseph Larmarange, Fern Terris-Prestholt
Summary: Despite progress in HIV status awareness in Cote d'Ivoire, Senegal, and Mali, there is still room for improvement. HIV self-testing was introduced as a new modality since 2019. Incorporating this service into civil society organization activities shows potential for substantial economies of scale and cost-effectiveness.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Marie P. Plaisy, Simon A. Boni, Patrick Coffie, Aristophane Tanon, Adoubi Innocent, Apollinaire Horo, Francois Dabis, Anne Bekelynck, Antoine Jaquet
Summary: In developing countries like Cote d'Ivoire, limited access to screening services for cervical cancer leads to a high prevalence of advanced stages at diagnosis. The study found that being HIV-negative and uninsured were independently associated with advanced cervical cancer. Qualitative data also highlighted the lack of information from healthcare providers and insufficient national awareness and screening campaigns as additional factors.
Article
Infectious Diseases
Idrissa Dieng, Moussa Moise Diagne, Marie Henriette Dior Ndione, Boris Gildas Hedible, Mamadou Diop, Edgard Valery Adjoguoua, Yahaya Sylla, Herve Kadjo, Cheikh Loucoubar, Amadou Alpha Sall, Oumar Faye, Ousmane Faye
Summary: Dengue fever is the most common arboviral infection worldwide, but its epidemiology in Africa is still not fully understood. This study reported a case of dengue virus serotype 2 imported from Cote d'Ivoire to Senegal, suggesting a possible spread of strains from the Burkina Faso outbreak to other West African countries. The phylogenetic analysis based on full-length genome sequence revealed a clustering with strains from the Burkina Faso outbreak in 2016 and the ongoing dengue fever outbreak in Cote d'Ivoire.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Oncology
Simon P. Boni, Franck Gnahatin, Jean-Claude Comoe, Boris Tchounga, Didier Ekouevi, Apollinaire Horo, Innocent Adoubi, Antoine Jaquet
Summary: Despite current initiatives to support awareness and prevention of cervical cancer in Abidjan, the screening uptake remains low. Factors associated with reported CC screening uptake include age, education level, and access to mass campaign information. Awareness campaigns need to be increased and tailored messages based on women's education level to enhance CC screening coverage and reach the WHO goal of CC elimination by 2030.
Article
Public, Environmental & Occupational Health
Odette Ky-Zerbo, Alice Desclaux, Alexis Brou Kouadio, Nicolas Rouveau, Anthony Vautier, Souleymane Sow, Sidi Cheick Camara, Sokhna Boye, Dolores Pourette, Younoussa Sidibe, Mathieu Maheu-Giroux, Joseph Larmarange
Summary: The stakeholders in the ATLAS project have positive perceptions about the introduction and integration of HIV self-testing, believing that it can reduce stigma, protect anonymity, and empower key populations. However, concerns remain about users' ability to correctly use the test kits and accept reactive results, indicating a need for reflective communication and local adaptation before implementation.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Nicolas Rouveau, Odette Ky-Zerbo, Sokhna Boye, Arlette Simo Fotso, Marc d'Elbee, Mathieu Maheu-Giroux, Romain Silhol, Arsene Kra Kouassi, Anthony Vautier, Clemence Doumenc-Aidara, Guillaume Breton, Abdelaye Keita, Eboi Ehui, Cheikh Tidiane Ndour, Marie-Claude Boilly, Fern Terris-Prestholt, Dolores Pourette, Alice Desclaux, Joseph Larmarange, Marie-Claude Boily
Summary: The ATLAS program aims to promote HIV self-testing in West Africa through multiple delivery channels, focusing on hard-to-reach populations. Research will assess the social, health, epidemiological effects, and cost-effectiveness of introducing HIVST in Cote d'Ivoire, Mali, and Senegal.
Article
Biotechnology & Applied Microbiology
Massara Camara-Cisse, Youzan Ferdinad Djohan, Thomas d'Aquin Toni, Jean-Jacques Renaud Dechi, Jean-Louis Philippe N'din, Esmel Essis Lohoues, Absalome Ake Monde, Leto Olivier Gogbe, Emmanuel Brou, Flore Fieni, Franck Adeoti Mansour, Roland Aby, Kouadio Kouakou, Henri Chenal
Summary: The study conducted in Cote d'Ivoire on HIV-1 infected children revealed a widespread resistance to reverse transcriptase inhibitors (RTIs), especially nucleoside reverse transcriptase inhibitors (NRTIs) and non-nucleoside reverse transcriptase inhibitors (NNRTIs). The high frequency of resistance mutations and the predominance of viral subtype CRF02_AG were observed, highlighting the importance of accessible monitoring of viral load and genotypic resistance tests in HIV-1 infected children undergoing treatment.
Article
Public, Environmental & Occupational Health
Arsene Kouassi Kra, Geraldine Colin, Papa Moussa Diop, Arlette Simo Fotso, Nicolas Rouveau, Kouakou Kouame Herve, Olivier Geoffroy, Bakary Diallo, Ode Kanku Kabemba, Baidy Dieng, Sanata Diallo, Anthony Vautier, Joseph Larmarange
Summary: The ATLAS program in Cote d'Ivoire, Mali, and Senegal encountered disruptions in HIVST distribution among key populations during the COVID-19 pandemic, but showed resilience and adaptation in the face of challenges. Monthly activity reports revealed a rebound in distribution numbers as the management of the pandemic improved, demonstrating the flexibility and learning capabilities of peer educators and key populations.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Multidisciplinary Sciences
Rachel D. Stelmach, Miriam Rabkin, Kouame Abo, Irma Ahoba, Mahena Gildas Anago, Rodrigo Boccanera, Hermann Brou, Rebecca Flueckiger, Kieran Hartsough, Martin Msukwa, Jennifer Zech, Felicity Young, Rachel Nugent
Summary: Despite the availability of free ART in Cote d'Ivoire, most participants still reported out-of-pocket spending on health care, with those with co-morbid NCDs experiencing higher costs.
Article
Immunology
Arlette Simo Fotso, Cheryl Johnson, Anthony Vautier, Konan Blaise Kouame, Papa Moussa Diop, Romain Silhol, Mathieu Maheu-Giroux, Marie-Claude Boily, Nicolas Rouveau, Clemence Doumenc-Aidara, Rachel Baggaley, Eboi Ehui, Joseph Larmarange
Summary: The distribution of ATLAS's HIV self-testing kits had a positive impact on HIV diagnoses, but had no significant effect on conventional testing uptake. This suggests that even if only a small portion of the distributed kits are used, HIVST can improve access to testing.
Letter
Rheumatology
Emilie Sbidian, Laetitia Penso, Philippe Herlemont, Jeremie Botton, Berangere Baricault, Laura Semenzato, Jerome Drouin, Alain Weill, Rosemay Dray-Spira, Mahmoud Zureik
ANNALS OF THE RHEUMATIC DISEASES
(2023)
Letter
Hematology
Clementine Vabre, Yoann Zelmat, Martin Gauthier, Marie Pajiep, Cecile Conte, Maryse Lapeyre-Mestre, Rosemary Dray-Spira, Mahmoud Zureik, Fabien Despas
AMERICAN JOURNAL OF HEMATOLOGY
(2022)
Review
Medicine, General & Internal
Marion Taine, Lucile Offredo, Alain Weill, Rosemary Dray-Spira, Mahmoud Zureik, Martin Chalumeau
Summary: This study found significant variations in pediatric outpatient prescriptions (POPs) between different countries, indicating the presence of inappropriate prescriptions. These findings may guide educational campaigns and regulatory decisions in some OECD member countries.
Article
Gastroenterology & Hepatology
Antoine Meyer, Paula Rios, Jerome Drouin, Alain Weill, Franck Carbonnel, Rosemary Dray-spira
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2023)
Article
Obstetrics & Gynecology
Noemie Roland, Berangere Baricault, Rosemary Dray-Spira, Alain Weill, Lise Duranteau, Mahmoud Zureik
Summary: This study assessed the user profiles and continuation rates of Cu-IUDs and LNG-IUSs in France in 2019. The findings indicate that LNG-IUS use is associated with being aged 35-44, receiving a prescription from a gynecologist, and having a gynecological history. Cu-IUDs have a higher continuation rate compared to LNG-IUSs.
INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS
(2023)
Article
Pharmacology & Pharmacy
Sarah Tubiana, Jeanne Sibiude, Philippe Herlemont, Jerome Drouin, Olivier Picone, Xavier Duval, Alain Weill, Mahmoud Zureik, Rosemary Dray-Spira
Summary: This study investigated the trends in anti-infective use during pregnancy from 2010 to 2019 using the French national health data system. The study found a decrease in the use of antibacterials and an increase in the use of antiviral agents. The study also suggested room for improvement in influenza vaccination.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2023)
Letter
Medicine, General & Internal
Noemie Roland, Berangere Baricault, Alain Weill, Kim Bouillon, Rosemary Dray-Spira, Lise Duranteau, Mahmoud Zureik
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Rheumatology
Laura Pina Vegas, Jerome Drouin, Rosemary Dray-Spira, Alain Weill
Summary: This study aimed to estimate the prevalence and mortality rate of rheumatoid arthritis (RA) in France and characterize the causes of death and prescribed treatments. The results showed a relatively low prevalence but higher mortality rate of RA in France, with increased mortality in cardiovascular, respiratory, digestive, urogenital diseases, and infections. Some patients were treated with conventional synthetic and biological/targeted synthetic disease-modifying antirheumatic drugs for RA.
Article
Pharmacology & Pharmacy
Mahmoud Zureik, Francois Cuenot, Alain Weill, Rosemary Dray-Spira
Summary: The French scientific group EPI-PHARE has reoriented its work to provide valuable insights to health authorities during the COVID-19 pandemic. By analyzing extensive data from the French Health Data System, EPI-PHARE has published numerous results on the use, benefits, and risks of medicines, as well as the risk factors associated with COVID-19 and the efficacy and risks of COVID-19 vaccines. These findings have played a significant role in informing decision-making and ensuring public health in France.
Article
Pharmacology & Pharmacy
Noemie Roland, Jerome Drouin, David Desplas, Lise Duranteau, Francois Cuenot, Rosemary Dray-Spira, Alain Weill, Mahmoud Zureik
Summary: This study assessed the impact of the COVID 19 pandemic on reimbursed contraceptives in France. After 15 months of the pandemic, a decrease in the dispensation of all reimbursed contraceptives was observed, with the greatest impact on women under 25 years old. These results highlight the need for long-term monitoring of contraceptive use and prioritizing access to sexual health services, especially for young women.
Article
Oncology
Kevin Jean, Ahmed Tawheed, Liem Binh Luong Nguyen, Tarek Heikal, Usama Eldaly, Neveen Elhadidy, Ahmed Elghaieb, Ahmed Aboudonia, Laura Tondeur, Amelie Dublineau, Arnaud Fontanet, Mohamed El-Kassas
Summary: This study aimed to assess temporal changes in the presentation and survival of patients with hepatocellular carcinoma (HCC) in northern Egypt, one of the regions with the highest incidence of the disease globally. The study found that although there was an increasing trend in early diagnosis of HCC, there was no significant improvement in overall survival over time.
JOURNAL OF HEPATOCELLULAR CARCINOMA
(2023)
Letter
Medicine, General & Internal
Marie-Joelle Jabagi, Marion Bertrand, Jeremie Botton, Stephane Le Vu, Alain Weill, Rosemary Dray-Spira, Mahmoud Zureik
Summary: In this French study, recipients of the bivalent vaccine and the original monovalent vaccine had similar risk of cardiovascular events 21 days after vaccination.
NEW ENGLAND JOURNAL OF MEDICINE
(2023)
Article
Pharmacology & Pharmacy
Sophie Billioti de Gage, Hugo Jourdain, David Desplas, Rosemary Dray-Spira
Summary: This article evaluates the roll-out and real-life effectiveness of oral HIV pre-exposure prophylaxis (PrEP) in France. The findings show that PrEP initiation increased steadily, but was significantly impacted by the COVID-19 pandemic. The majority of PrEP users were men living in urban areas. Adherence to PrEP was generally high, but a substantial proportion of early treatment discontinuation was observed. Overall PrEP effectiveness was 60%, but varied among different population groups.
Article
Immunology
Haoyi Wang, Jean-Michel Molina, Rosemary Dray-Spira, Axel J. Schmidt, Ford Hickson, David van de Vijver, Kai J. Jonas
Summary: This study used national pharmaco-epidemiology surveillance data and regional MSM population estimations to model the spatio-temporal distribution of PrEP uptake among MSM in France 2016-2021 to identify marginalized MSM at risk for HIV and increase their PrEP uptake.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY
(2023)
Article
Multidisciplinary Sciences
Moussa Laanani, Alain Weill, Fabrice Jollant, Mahmoud Zureik, Rosemary Dray-Spira
Summary: A nationwide cohort study in France found that finasteride, a 5 alpha-reductase inhibitor used in the treatment of benign prostatic hyperplasia, may be associated with an increased risk of suicide, particularly among individuals with a history of mood disorders.
SCIENTIFIC REPORTS
(2023)