Low Level Sequence Variant Analysis of Recombinant Proteins: An Optimized Approach

Antibody-based therapeutics to watch in 2011

(2011) Janice M. Reichert   mAbs

Analysis of monoclonal antibody product heterogeneity resulting from alternate cleavage sites of signal peptide

(2010) Ruchi B. Kotia et al.   ANALYTICAL BIOCHEMISTRY

Control of misincorporation of serine for asparagine during antibody production using CHO cells

(2010) Anurag Khetan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Mechanisms of unintended amino acid sequence changes in recombinant monoclonal antibodies expressed in Chinese Hamster Ovary (CHO) cells

(2010) Donglin Guo et al.   BIOTECHNOLOGY AND BIOENGINEERING

Industrialization of mAb production technology: The bioprocessing industry at a crossroads

(2010) Brian Kelley   mAbs

Detecting low level sequence variants in recombinant monoclonal antibodies

(2010) Yi Yang et al.   mAbs

Recent advances in large-scale production of monoclonal antibodies and related proteins

(2010) Abhinav A. Shukla et al.   TRENDS IN BIOTECHNOLOGY

Identification of Codon-Specific Serine to Asparagine Mistranslation in Recombinant Monoclonal Antibodies by High-Resolution Mass Spectrometry

(2009) X. Christopher Yu et al.   ANALYTICAL CHEMISTRY

Challenges in monoclonal antibody-based therapies

(2009) Haritha Samaranayake et al.   ANNALS OF MEDICINE

Enhanced antibody production following intermediate addition based on flux analysis in mammalian cell continuous culture

(2009) Takeshi Omasa et al.   BIOPROCESS AND BIOSYSTEMS ENGINEERING

Expression systems for therapeutic glycoprotein production

(2009) Yves Durocher et al.   CURRENT OPINION IN BIOTECHNOLOGY

Discovery and Investigation of Misincorporation of Serine at Asparagine Positions in Recombinant Proteins Expressed in Chinese Hamster Ovary Cells

(2009) Dingyi Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Monoclonal Antibodies as Innovative Therapeutics

(2008) Janice Reichert   CURRENT PHARMACEUTICAL BIOTECHNOLOGY