The Crystal Structures of Dystrophin and Utrophin Spectrin Repeats: Implications for Domain Boundaries

Internal deletion compromises the stability of dystrophin

(2011) Davin M. Henderson et al.   HUMAN MOLECULAR GENETICS

Crystal Structure of a Rigid Four-Spectrin-Repeat Fragment of the Human Desmoplakin Plakin Domain

(2011) Hee-Jung Choi et al.   JOURNAL OF MOLECULAR BIOLOGY

A biophysical map of the dystrophin rod

(2010) Ahmed Mirza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids

(2010) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

ALINE: a WYSIWYG protein-sequence alignment editor for publication-quality alignments

(2009) Charles Simon Bond et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The 8th and 9th tandem spectrin-like repeats of utrophin cooperatively form a functional unit to interact with polarity-regulating kinase PAR-1b

(2009) Kazunari Yamashita et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The artificial gene Jazz, a transcriptional regulator of utrophin, corrects the dystrophic pathology in mdx mice

(2009) Maria Grazia Di Certo et al.   HUMAN MOLECULAR GENETICS

Pharmacological activation of PPAR /  stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice

(2009) P. Miura et al.   HUMAN MOLECULAR GENETICS

Skeletal dysplasias due to filamin A mutations result from a gain-of-function mechanism distinct from allelic neurological disorders†

(2009) Alice R. Clark et al.   HUMAN MOLECULAR GENETICS

A Two-amino Acid Mutation Encountered in Duchenne Muscular Dystrophy Decreases Stability of the Rod Domain 23 (R23) Spectrin-like Repeat of Dystrophin

(2009) Sébastien Legardinier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dystrophins carrying spectrin-like repeats 16 and 17 anchor nNOS to the sarcolemma and enhance exercise performance in a mouse model of muscular dystrophy

(2009) Yi Lai et al.   JOURNAL OF CLINICAL INVESTIGATION

Disease-associated Substitutions in the Filamin B Actin Binding Domain Confer Enhanced Actin Binding Affinity in the Absence of Major Structural Disturbance: Insights from the Crystal Structures of Filamin B Actin Binding Domains

(2009) Gregory M. Sawyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Mapping of the Lipid-Binding and Stability Properties of the Central Rod Domain of Human Dystrophin

(2009) Sébastien Legardinier et al.   JOURNAL OF MOLECULAR BIOLOGY

Dystrophin and utrophin have distinct effects on the structural dynamics of actin

(2009) E. Prochniewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Muscle Degeneration, Regeneration, and Repair in the Muscular Dystrophies

(2008) Gregory Q. Wallace et al.   Annual Review of Physiology

Searching protein structure databases with DaliLite v.3

(2008) L. Holm et al.   BIOINFORMATICS