Article
Medicine, General & Internal
Nadia Ali, Amanda Caceres, Eric W. Hall, Dawn Laney
Summary: This pilot study compared reported symptoms of attention-deficit/hyperactivity in adults with Fabry disease with normative control data, finding a higher prevalence of symptoms in Fabry disease patients. The study suggests that attention difficulties in Fabry disease patients are not solely explained by ADHD. Patients reporting symptoms were also more likely to report difficulties in adaptive functioning.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Psychology, Multidisciplinary
Erica D. Musser, Stephanie S. J. Morris, Kathleen Feeney, Rosario Pintos Lobo, Edward F. Ester
Summary: Inattention is a key symptom of ADHD, but the mechanisms underlying it are unclear. More specific approaches are needed to link disruptions in cognitive performance with ADHD behaviors. A pilot study found that even typically developing children did not maximally extract and combine information to maximize rewards in a cognitive task targeting attention selection mechanisms.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Biochemistry & Molecular Biology
E. M. Bruxel, C. R. Moreira-Maia, G. C. Akutagava-Martins, T. P. Quinn, M. Klein, B. Franke, M. Ribases, P. Rovira, C. Sanchez-Mora, D. B. Kappel, N. R. Mota, E. H. Grevet, C. H. D. Bau, M. Arcos-Burgos, L. A. Rohde, M. H. Hutz
Summary: This study conducted a meta-analysis to investigate the association between ADGRL3 gene variants and ADHD susceptibility in children and adults, finding significant correlation in children but not in adults. The results suggest that ADGRL3 gene is predominantly associated with childhood ADHD.
MOLECULAR PSYCHIATRY
(2021)
Article
Medicine, General & Internal
Johannes Lieslehto, Jari Tiihonen, Markku Laehteenvuo, Ellenor Mittendorfer-Rutz, Antti Tanskanen, Heidi Taipale
Summary: This study investigated the impact of pharmacotherapy on suicide risk in patients with borderline personality disorder (BPD). The results indicated that ADHD medication may reduce the risk of suicide, while mood stabilizers and antidepressants may increase the risk. The findings suggest that benzodiazepines should be used with caution due to their association with increased suicide risk in patients with BPD.
Article
Multidisciplinary Sciences
Revital Hamerman, Noga Cohen
Summary: Previous research has shown that training individuals to recruit cognitive control before exposure to negative pictures can increase the likelihood of using reappraisal and achieving success. This study found that individuals with high ADHD symptoms were more likely to use reappraisal after training and experienced a greater reduction in negative emotions.
SCIENTIFIC REPORTS
(2022)
Review
Clinical Neurology
Shun Wang, Baozhen Yao, Haiju Zhang, Liping Xia, Shiqian Yu, Xia Peng, Dan Xiang, Zhongchun Liu
Summary: Epilepsy and attention-deficit/hyperactivity disorder (ADHD) are common neurological and neuropsychiatric disorders, and they can coexist. However, the degree of comorbidity between both disorders has never been quantified. A meta-analysis of 63 studies with over 1 million individuals from 17 countries revealed that the pooled prevalence of ADHD in epilepsy was 22.3%, while the pooled prevalence of epilepsy in ADHD was 3.4%. Factors such as sample size, specification, geographical variations, and diagnostic methods contributed to the observed heterogeneity in comorbidity rates. Further research is needed to understand the underlying mechanisms.
JOURNAL OF NEUROLOGY
(2023)
Article
Neurosciences
Markus Koelle, Sarah Mackert, Katharina Heckel, Alexandra Philipsen, Martin Ulrich, Georg Groen
Summary: This study found an association between RTV and white matter structural properties of the corticothalamic tract in adults with ADHD, which was not observed in healthy controls.
JOURNAL OF PSYCHIATRY & NEUROSCIENCE
(2022)
Article
Pediatrics
Christine Strand Bachmann, Kari Risnes, Johan Hakon Bjorngaard, Jorun Schei, Kristine Pape
Summary: The study examines the impact of relative age on mental health, specifically in preterm infants. The results show that being relatively young within a school class is associated with an increased likelihood of psychostimulant prescription, and this effect persists into young adulthood for preterm individuals.
Article
Pediatrics
Bezawit E. Kase, Nanda Rommelse, Qi Chen, Lin Li, Anneli Andersson, Ebba Du Rietz, Melissa Vos, Samuele Cortese, Henrik Larsson, Catharina A. Hartman
Summary: This study found a stable link between ADHD symptoms and BMI during adolescence, primarily with hyperactive and impulsive symptoms rather than inattention. No direct effects were found between ADHD symptoms and BMI increase or enhanced ADHD symptoms due to BMI during this period.
Article
Multidisciplinary Sciences
Amy M. Ni, Brittany S. Bowes, Douglas A. Ruff, Marlene R. Cohen
Summary: Most systems neuroscience studies can be categorized into basic science work and translational work. This study combines these two approaches and reveals that orally administered methylphenidate enhances spatially selective visual attention and improves visual performance. Furthermore, it suggests that decreased correlated variability of neurons may be a general mechanism for treating neuropsychiatric disorders.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Psychology, Clinical
E. Martin, C. T. Dourish, R. Hook, S. R. Chamberlain, S. Higgs
Summary: The study found that symptoms of ADHD and impulsivity are associated with disordered eating, and depression plays a mediating role in this relationship.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Microbiology
Yoon Jae Cho, Bokyoung Shin, Sung-Ha Lee, Sangmin Park, Yoon-Keun Kim, Jae-Jin Kim, Eunjoo Kim
Summary: This study analyzed urine microbiome profiles to explore the potential of the urine microbiome as a biomarker for pediatric ADHD. The ADHD group showed decreased alpha diversity and significant beta diversity differences compared to the control group. The genus Afipia exhibited significant correlations with ADHD symptoms, suggesting its potential as a biomarker for ADHD.
Article
Nutrition & Dietetics
Yushan Zhang, Zhaohuan Gui, Nan Jiang, Xueya Pu, Meiling Liu, Yingqi Pu, Shan Huang, Shaoyi Huang, Yajun Chen
Summary: Consumption of sugar-sweetened beverages (SSBs) has increased significantly and may lead to various health problems. Studies on the association between SSBs and attention-deficit/hyperactivity disorder (ADHD) in children are limited and inconsistent. We conducted a study on 6541 students aged 6-12, using a two-stage cluster sampling method. Our findings suggest that SSB intake is positively correlated with the risk of hyperactivity in children.
Article
Neurosciences
Gustavo Sudre, Marine Bouyssi-Kobar, Luke Norman, Wendy Sharp, Saadia Choudhury, Philip Shaw
Summary: The study found significant heritability in the rates of change of white matter tract microstructural properties and connectivity between different brain networks. Changes in hyperactivity-impulsivity were associated with heritable changes in white matter tracts metrics and connectivity between attention and cognitive networks. This suggests that these heritable ADHD-associated neural phenotypes can be useful for future gene discovery and understanding.
BIOLOGICAL PSYCHIATRY
(2021)
Article
Immunology
Ching-Shu Tsai, Ray C. Hsiao, Yu-Min Chen, Cheng-Fang Yen
Summary: A study found that 25.5% of caregivers were hesitant to vaccinate their children with ADHD against COVID-19, while 11.8% refused to vaccinate. Caregivers' concerns about vaccine safety and children's regular use of medication for ADHD were negatively associated with intentions to vaccinate, while children's comorbid conduct issues were positively associated.
Article
Oncology
Pierre-Yves Fortin, Matthieu Lepetit-Coiffe, Coralie Genevois, Christelle Debeissat, Bruno Quesson, Chrit T. W. Moonen, Jan Pieter Konsman, Franck Couillaud
Article
Neurosciences
Lea Chaskiel, Flora Paul, Ruediger Gerstberger, Thomas Huebschle, Jan Pieter Konsman
Review
Neurosciences
Beatriz Rodriguez-Grande, Jan-Pieter Konsman
JOURNAL OF NEUROSCIENCE RESEARCH
(2018)
Article
Biochemistry & Molecular Biology
Aleksandra Ichkova, Beatriz Rodriguez-Grande, Claire Bar, Frederic Villega, Jan Pieter Konsman, Jerome Badaut
NEUROCHEMISTRY INTERNATIONAL
(2017)
Article
Neurosciences
Frederic Villega, Jean-Christophe Delpech, Marion Griton, Caroline Andre, Jean-Michel Franconi, Sylvain Miraux, Jan Pieter Konsman
Review
Clinical Neurology
Marion Griton, Jan Pieter Konsman
CLINICAL AUTONOMIC RESEARCH
(2018)
Article
Immunology
Ibtihel Dhaya, Marion Griton, Gerard Raffard, Mohamed Amri, Bassem Hiba, Jan Pieter Konsman
JOURNAL OF NEUROIMMUNOLOGY
(2018)
Article
Psychology, Biological
Katarzyna B. Hooks, Jan Pieter Konsman, Maureen A. O'Malley
BEHAVIORAL AND BRAIN SCIENCES
(2019)
Article
Pharmacology & Pharmacy
Floor van Heesch, Jolanda Prins, Jan Pieter Konsman, Gerdien A. H. Korte-Bouws, Koen G. C. Westphal, Joanna Rybka, Berend Olivier, Aletta D. Kraneveld, S. Mechiel Korte
EUROPEAN JOURNAL OF PHARMACOLOGY
(2014)
Article
Plant Sciences
Merian Nassra, Stephanie Krisa, Yorgos Papastamoulis, Gilbert Deccaux Kapche, Jonathan Bisson, Caroline Andre, Jan-Pieter Konsman, Jean-Marie Schmitter, Jean-Michel Merillon, Pierre Waffo-Teguo
Article
Chemistry, Medicinal
Jan Pieter Konsman
Summary: Despite the protective tissues and barriers in the brain, certain injuries or infections can lead to changes in brain function and behavior due to cytokine production and action. Peripheral infection-induced inflammation and psychological stress may also have similar effects on the central nervous system. Understanding the conditions of cytokine production and action in the brain is important for studying neuroinflammation and exploring ways to modify neural functioning.
Article
Chemistry, Medicinal
Lea Chaskiel, Robert Dantzer, Jan Konsman
Summary: The study investigated the role of brain perivascular macrophages in mediating IL-1 beta-induced sickness behavior in rats, showing that targeting these cells through intracerebroventricular (icv) administration of IL-1 beta-saporin is an effective method to study their involvement.
Article
Biochemistry & Molecular Biology
Ibtihel Dhaya, Marion Griton, Jan Pieter Konsman
Summary: In this study, it was found that MRI under isoflurane anesthesia in rodents can alter neurovascular and glial responses, indicating that the results should be interpreted with caution.
ANIMAL MODELS AND EXPERIMENTAL MEDICINE
(2021)
Review
Chemistry, Medicinal
Jan Pieter Konsman
Article
Communication
Melanie Bourdaa, Jan Pieter Konsman, Claire Secail, Tommaso Venturini, Isabelle Veyrat-Masson, Francois Gonon
PUBLIC UNDERSTANDING OF SCIENCE
(2015)