A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity

Title
A Novel Small Molecule FL118 That Selectively Inhibits Survivin, Mcl-1, XIAP and cIAP2 in a p53-Independent Manner, Shows Superior Antitumor Activity
Authors
Keywords
Cancer treatment, Apoptosis, Mouse models, Luciferase, Colorectal cancer, Flow cytometry, Colon, Cell growth
Journal
PLoS One
Volume 7, Issue 9, Pages e45571
Publisher
Public Library of Science (PLoS)
Online
2012-09-20
DOI
10.1371/journal.pone.0045571

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