Activation of BKCa Channels in Zoledronic Acid-Induced Apoptosis of MDA-MB-231 Breast Cancer Cells

Targeting the extrinsic apoptosis signaling pathway for cancer therapy

(2011) Thomas J. Sayers   CANCER IMMUNOLOGY IMMUNOTHERAPY

Direct antitumour activity of zoledronic acid: preclinical and clinical data

(2011) Joaquim Bosch-Barrera et al.   Clinical & Translational Oncology

Differential Regulation and Recovery of Intracellular Ca2+ in Cerebral and Small Mesenteric Arterial Smooth Muscle Cells of Simulated Microgravity Rat

(2011) Jun-Hui Xue et al.   PLoS One

Activation of BKCa channel is associated with increased apoptosis of cerebrovascular smooth muscle cells in simulated microgravity rats

(2010) Man-Jiang Xie et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Anticancer Properties of Zoledronic Acid

(2010) Jonathan Green et al.   CANCER INVESTIGATION

Bisphosphonates and RANK ligand inhibitors for the treatment and prevention of metastatic bone disease

(2010) H.L. Neville-Webbe et al.   EUROPEAN JOURNAL OF CANCER

Large conductance, Ca2+ -activated K+ channels (BKCa ) and arteriolar myogenic signaling

(2010) Michael A. Hill et al.   FEBS LETTERS

High glucose alters apoptosis and proliferation in HEK293 cells by inhibition of cloned BKCa channel

(2010) Hui Chang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium

(2010) Jiusheng Yan et al.   NATURE

Calcium-Activated Potassium Channels BK and IK1 Are Functionally Expressed in Human Gliomas but Do Not Regulate Cell Proliferation

(2010) Iskandar F. Abdullaev et al.   PLoS One

BK channel activation: structural and functional insights

(2010) Urvi S. Lee et al.   TRENDS IN NEUROSCIENCES

Activation of cloned BKCa channels in nitric oxide-induced apoptosis of HEK293 cells

(2009) Yu-Guang Ma et al.   APOPTOSIS

Role of KCNMA1gene in breast cancer invasion and metastasis to brain

(2009) Divya Khaitan et al.   BMC CANCER

The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro

(2009) Laura M. Mitrofan et al.   BONE

Coexpression and characterization of the human large-conductance Ca2+-activated K+ channel α + β1 subunits in HEK293 cells

(2009) Jun Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Endocrine Therapy plus Zoledronic Acid in Premenopausal Breast Cancer

(2009) Michael Gnant et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APCMin/+ mice

(2009) G E Koehl et al.   ONCOGENE

Modulation of BKCa Channel Gating by Endogenous Signaling Molecules

(2009) Shangwei Hou et al.   PHYSIOLOGY

The potassium ion channel opener NS1619 inhibits proliferation and induces apoptosis in A2780 ovarian cancer cells

(2008) Xiaobing Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antitumor effects of bisphosphonates: Promising preclinical evidence

(2008) Theresa A. Guise   CANCER TREATMENT REVIEWS

An Unexpected Role for Ion Channels in Brain Tumor Metastasis

(2008) Harald Sontheimer   EXPERIMENTAL BIOLOGY AND MEDICINE

Mechanisms of the Action of Zoledronic Acid on Human MG-63 Osteosarcoma Cells

(2008) R. Tenta et al.   HORMONE AND METABOLIC RESEARCH

Silencing of hSlo potassium channels in human osteosarcoma cells promotes tumorigenesis

(2008) Béatrice Cambien et al.   INTERNATIONAL JOURNAL OF CANCER

Antitumor Effects of Doxorubicin Followed by Zoledronic Acid in a Mouse Model of Breast Cancer

(2008) P. D. Ottewell et al.   JNCI-Journal of the National Cancer Institute

Potassium channels in the regulation of pulmonary artery smooth muscle cell proliferation and apoptosis: pharmacotherapeutic implications

(2007) E D Burg et al.   BRITISH JOURNAL OF PHARMACOLOGY