Untargeted Plasma Metabolite Profiling Reveals the Broad Systemic Consequences of Xanthine Oxidoreductase Inactivation in Mice

MetSign: A Computational Platform for High-Resolution Mass Spectrometry-Based Metabolomics

(2011) Xiaoli Wei et al.   ANALYTICAL CHEMISTRY

Metabolomics for mitochondrial and cancer studies

(2011) Deepak Nagrath et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Xanthine oxidoreductase: A journey from purine metabolism to cardiovascular excitation-contraction coupling

(2011) Amit Agarwal et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Metabolomics, Pathway Regulation, and Pathway Discovery

(2011) Guo-Fang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Capillary electrophoresis as a metabolomics tool for non-targeted fingerprinting of biological samples

(2011) C. Barbas et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Contribution of Xanthine Oxidoreductase to Mammary Epithelial and Breast Cancer Cell Differentiation In Part Modulates Inhibitor of Differentiation-1

(2011) M. A. Fini et al.   MOLECULAR CANCER RESEARCH

Urine metabolomics for kidney cancer detection and biomarker discovery

(2011) Sheila Ganti et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Advances in mass spectrometry applied to pharmaceutical metabolomics

(2010) Dieter M. Drexler et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

The role of metabolites and metabolomics in clinically applicable biomarkers of disease

(2010) Mamas Mamas et al.   ARCHIVES OF TOXICOLOGY

Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review

(2010) Aurélie Roux et al.   CLINICAL BIOCHEMISTRY

Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk

(2010) M. Goicoechea et al.   Clinical Journal of the American Society of Nephrology

Metabolomics in systems microbiology

(2010) Marshall Louis Reaves et al.   CURRENT OPINION IN BIOTECHNOLOGY

Xanthine Oxidoreductase Promotes the Inflammatory State of Mononuclear Phagocytes through Effects on Chemokine Expression, Peroxisome Proliferator-activated Receptor-γ Sumoylation, and HIF-1α

(2010) Sophie Gibbings et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combination of thiopurines and allopurinol: Adverse events and clinical benefit in IBD

(2010) Shail M. Govani et al.   Journal of Crohns & Colitis

Effect of high-dose allopurinol on exercise in patients with chronic stable angina: a randomised, placebo controlled crossover trial

(2010) Awsan Noman et al.   LANCET

Prognostic value of xanthine oxidoreductase expression in patients with non-small cell lung cancer

(2010) Anthony W. Kim et al.   LUNG CANCER

Enhanced xanthine oxidoreductase expression and tissue nitrate reduction in germ free mice

(2010) Liyue Huang et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

The role of urate and xanthine oxidase in vascular oxidative stress: future directions

(2010) Jacob George   Therapeutics and Clinical Risk Management

Urinary L-Type Fatty Acid-Binding Protein Can Reflect Renal Tubulointerstitial Injury

(2009) Tamami Tanaka et al.   AMERICAN JOURNAL OF PATHOLOGY

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

The effect of allopurinol on the cerebral vasculature of patients with subcortical stroke; a randomized trial

(2009) Jesse Dawson et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

(2009) F. C. Barreto et al.   Clinical Journal of the American Society of Nephrology

Update on emerging urate-lowering therapies

(2009) Saima Chohan et al.   CURRENT OPINION IN RHEUMATOLOGY

Xanthine Oxidoreductase Depletion Induces Renal Interstitial Fibrosis Through Aberrant Lipid and Purine Accumulation in Renal Tubules

(2009) Toshio Ohtsubo et al.   HYPERTENSION

UPLC-MS-Based Analysis of Human Plasma for Metabonomics Using Solvent Precipitation or Solid Phase Extraction

(2009) Filippos Michopoulos et al.   JOURNAL OF PROTEOME RESEARCH

Analysis of hydrophilic metabolites in physiological fluids by HPLC-MS using a silica hydride-based stationary phase

(2009) Joseph J. Pesek et al.   JOURNAL OF SEPARATION SCIENCE

Suitability of silica hydride stationary phase, aqueous normal phase chromatography for untargeted metabolomic profiling of Enterococcus faecium and Staphylococcus aureus

(2009) Scott A. Weisenberg et al.   JOURNAL OF SEPARATION SCIENCE

Analytical and statistical approaches to metabolomics research

(2009) Haleem J. Issaq et al.   JOURNAL OF SEPARATION SCIENCE

Metabolomic applications of HILIC-LC-MS

(2009) Simon Cubbon et al.   MASS SPECTROMETRY REVIEWS

Post-reductionist protein science, or putting Humpty Dumpty back together again

(2009) Lila M Gierasch et al.   Nature Chemical Biology

Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms

(2009) J. C. Schefold et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Allopurinol-Induced DRESS Syndrome in an Adolescent Patient

(2009) Ashvin K. Dewan et al.   PEDIATRIC DERMATOLOGY

Mechanisms Underlying Erythrocyte and Endothelial Nitrite Reduction to Nitric Oxide in Hypoxia

(2008) Andrew J. Webb et al.   CIRCULATION RESEARCH

Metabolomic profiling ofDrosophilausing liquid chromatography Fourier transform mass spectrometry

(2008) M.A. Kamleh et al.   FEBS LETTERS

A sample extraction and chromatographic strategy for increasing LC/MS detection coverage of the erythrocyte metabolome

(2008) Theodore R. Sana et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES