JNK3 Maintains Expression of the Insulin Receptor Substrate 2 (IRS2) in Insulin-Secreting Cells: Functional Consequences for Insulin Signaling

FoxO Feedback Control of Basal IRS-2 Expression in Pancreatic β-Cells Is Distinct From That in Hepatocytes

(2011) Shin Tsunekawa et al.   DIABETES

Glucose and Fatty Acids Synergize to Promote B-Cell Apoptosis through Activation of Glycogen Synthase Kinase 3β Independent of JNK Activation

(2011) Katsuya Tanabe et al.   PLoS One

Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice

(2010) Y. Liu et al.   DIABETOLOGIA

Exendin-4 Protects Oxidative Stress-Induced β-Cell Apoptosis through Reduced JNK and GSK3β Activity

(2010) Ju-Young Kim et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis

(2009) S. Abdelli et al.   DIABETOLOGIA

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance

(2008) Katsuya Tanabe et al.   PLOS BIOLOGY