A Transplantable Phosphorylation Probe for Direct Assessment of G Protein-Coupled Receptor Activation

DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours

(2011) U Plöckinger et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Differential Temporal and Spatial Regulation of Somatostatin Receptor Phosphorylation and Dephosphorylation

(2011) Madhumita Ghosh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal structure of the β2 adrenergic receptor–Gs protein complex

(2011) Søren G. F. Rasmussen et al.   NATURE

Structural insights into adrenergic receptor function and pharmacology

(2011) Brian K. Kobilka   TRENDS IN PHARMACOLOGICAL SCIENCES

Pasireotide (SOM230) Demonstrates Efficacy and Safety in Patients with Acromegaly: A Randomized, Multicenter, Phase II Trial

(2010) S. Petersenn et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pasireotide and Octreotide Stimulate Distinct Patterns of sst2ASomatostatin Receptor Phosphorylation

(2010) Florian Pöll et al.   MOLECULAR ENDOCRINOLOGY

Medical Treatment of Cushing’s Disease: Somatostatin Analogues and Pasireotide

(2010) Alberto M. Pedroncelli   NEUROENDOCRINOLOGY

Sensing G protein-coupled receptor activation

(2010) Manuela Ambrosio et al.   NEUROPHARMACOLOGY

Site Specificity of Agonist and Second Messenger-Activated Kinases for Somatostatin Receptor Subtype 2A (Sst2A) Phosphorylation

(2009) Q. Liu et al.   MOLECULAR PHARMACOLOGY

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

Reassessment of sst2Somatostatin Receptor Expression in Human Normal and Neoplastic Tissues Using the Novel Rabbit Monoclonal Antibody UMB-1

(2008) Thomas Fischer et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Selective Loss of Somatostatin Receptor 2 in Octreotide-Resistant Growth Hormone-Secreting Adenomas

(2008) Ursula Plöckinger et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Treatment of Pituitary-Dependent Cushing’s Disease with the Multireceptor Ligand Somatostatin Analog Pasireotide (SOM230): A Multicenter, Phase II Trial

(2008) M. Boscaro et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Differential Effects of Octreotide and Pasireotide on Somatostatin Receptor Internalization and Traffickingin Vitro

(2008) Sarah Lesche et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Conformational changes involved in G-protein-coupled-receptor activation

(2008) Jürgen Wess et al.   TRENDS IN PHARMACOLOGICAL SCIENCES