Glycogen Synthase Kinase 3 (GSK3) Inhibitor, SB-216763, Promotes Pluripotency in Mouse Embryonic Stem Cells

A Tcf/Lef element within the enhancer region of the human NANOG gene plays a role in promoter activation

(2011) Chang Gun Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

β-Catenin Enhances Oct-4 Activity and Reinforces Pluripotency through a TCF-Independent Mechanism

(2011) Kevin F. Kelly et al.   Cell Stem Cell

Maintaining embryonic stem cell pluripotency with Wnt signaling

(2011) S. Y. Sokol   DEVELOPMENT

Wnt: What's Needed To maintain pluripotency?

(2011) Hitoshi Niwa   NATURE CELL BIOLOGY

Differential requirement for the dual functions of β-catenin in embryonic stem cell self-renewal and germ layer formation

(2011) Natalia Lyashenko et al.   NATURE CELL BIOLOGY

Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal

(2011) Fei Yi et al.   NATURE CELL BIOLOGY

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

(2011) Jason Wray et al.   NATURE CELL BIOLOGY

Id1 Maintains Embryonic Stem Cell Self-Renewal by Up-Regulation of Nanog and Repression of Brachyury Expression

(2011) Elizabeth E. Romero-Lanman et al.   STEM CELLS AND DEVELOPMENT

Chemical Control of Stem Cell Fate and Developmental Potential

(2010) Costas A. Lyssiotis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Homeodomain-interacting protein kinase 2 (HIPK2) targets β-catenin for phosphorylation and proteasomal degradation

(2010) Eun-A Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of GSK3β enhances both adhesive and signalling activities of β-catenin in mouse embryonic stem cells

(2010) Galina S. Sineva et al.   BIOLOGY OF THE CELL

A Murine ESC-like State Facilitates Transgenesis and Homologous Recombination in Human Pluripotent Stem Cells

(2010) Christa Buecker et al.   Cell Stem Cell

Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

(2010) Marc P. M. Soutar et al.   JOURNAL OF NEUROCHEMISTRY

Extrinsic regulation of pluripotent stem cells

(2010) Martin F. Pera et al.   NATURE

Canonical Wnt/β-Catenin Regulation of Liver Receptor Homolog-1 Mediates Pluripotency Gene Expression

(2010) Ryan T. Wagner et al.   STEM CELLS

Involvement of GSK-3 in Regulation of Murine Embryonic Stem Cell Self-Renewal Revealed by a Series of Bisindolylmaleimides

(2009) Heather K. Bone et al.   CHEMISTRY & BIOLOGY

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

(2009) Bryan T. MacDonald et al.   DEVELOPMENTAL CELL

A parallel circuit of LIF signalling pathways maintains pluripotency of mouse ES cells

(2009) Hitoshi Niwa et al.   NATURE

GATA4 is a regulator of astrocyte cell proliferation and apoptosis in the human and murine central nervous system

(2009) S Agnihotri et al.   ONCOGENE

Small molecules that modulate embryonic stem cell fate and somatic cell reprogramming

(2009) Wenlin Li et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Capturing Pluripotency

(2008) Jose Silva et al.   CELL

Tcf3 is an integral component of the core regulatory circuitry of embryonic stem cells

(2008) M. F. Cole et al.   GENES & DEVELOPMENT

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of  -catenin in mice

(2008) T. Grigoryan et al.   GENES & DEVELOPMENT

The ground state of embryonic stem cell self-renewal

(2008) Qi-Long Ying et al.   NATURE

T-Cell Factor 3 Regulates Embryonic Stem Cell Pluripotency and Self-Renewal by the Transcriptional Control of Multiple Lineage Pathways

(2008) Wai-Leong Tam et al.   STEM CELLS

Analysis of the Factors that Limit the Ability of Feeder Cells to Maintain the Undifferentiated State of Human Embryonic Stem Cells

(2008) Luis G. Villa-Diaz et al.   STEM CELLS AND DEVELOPMENT