Targeting Sphingosine Kinase 1 in Carcinoma Cells Decreases Proliferation and Survival by Compromising PKC Activity and Cytokinesis

Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer

(2011) Dmitri Pchejetski et al.   Nature Reviews Urology

S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism

(2011) A Kumar et al.   Cell Death & Disease

Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage

(2010) Andrea Huwiler et al.   BRITISH JOURNAL OF PHARMACOLOGY

Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos

(2010) Ilio Vitale et al.   EMBO JOURNAL

The Sphingosine Kinase 1 Inhibitor 2-(p-Hydroxyanilino)-4-(p-chlorophenyl)thiazole Induces Proteasomal Degradation of Sphingosine Kinase 1 in Mammalian Cells

(2010) Carolyn Loveridge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Export and functions of sphingosine-1-phosphate

(2009) Roger H. Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The sphingosine 1-phosphate receptor 5 and sphingosine kinases 1 and 2 are localised in centrosomes: Possible role in regulating cell division

(2009) Laura Gillies et al.   CELLULAR SIGNALLING

The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis

(2009) S. Peddibhotla et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner

(2008) Lotte P. Hofmann et al.   BIOLOGICAL CHEMISTRY

Role for sphingosine kinase 1 in colon carcinogenesis

(2008) Toshihiko Kawamori et al.   FASEB JOURNAL

The regulated assembly of a PKCɛ complex controls the completion of cytokinesis

(2008) Adrian T. Saurin et al.   NATURE CELL BIOLOGY