Tibial Loading Increases Osteogenic Gene Expression and Cortical Bone Volume in Mature and Middle-Aged Mice
Published 2012 View Full Article
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Title
Tibial Loading Increases Osteogenic Gene Expression and Cortical Bone Volume in Mature and Middle-Aged Mice
Authors
Keywords
Tibia, Gene expression, Bone development, Age groups, Bone and joint mechanics, Aging, Compression, Legs
Journal
PLoS One
Volume 7, Issue 4, Pages e34980
Publisher
Public Library of Science (PLoS)
Online
2012-04-14
DOI
10.1371/journal.pone.0034980
References
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Related references
Note: Only part of the references are listed.- Tibial compression is anabolic in the adult mouse skeleton despite reduced responsiveness with aging
- (2011) Maureen E. Lynch et al. BONE
- Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone
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- (2010) Jennifer A. McKenzie et al. BONE
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- Age-Related Changes in Bone Structure and Strength in Female and Male BALB/c Mice
- (2010) Mark D. Willinghamm et al. CALCIFIED TISSUE INTERNATIONAL
- Cancellous bone adaptation to tibial compression is not sex dependent in growing mice
- (2010) Maureen E. Lynch et al. JOURNAL OF APPLIED PHYSIOLOGY
- Aging changes mechanical loading thresholds for bone formation in rats
- (2010) Charles H. Turner et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Aged mice have enhanced endocortical response and normal periosteal response compared with young-adult mice following 1 week of axial tibial compression
- (2010) Michael D Brodt et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Gene expression patterns in bone following mechanical loading
- (2010) Sara M Mantila Roosa et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Mechanical signals as anabolic agents in bone
- (2010) Engin Ozcivici et al. Nature Reviews Rheumatology
- Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor α and disuse
- (2009) Gul Zaman et al. BONE
- Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1–34) on trabecular and cortical bone in mice
- (2008) Toshihiro Sugiyama et al. BONE
- Bone Mass Is Preserved and Cancellous Architecture Altered Due to Cyclic Loading of the Mouse Tibia After Orchidectomy
- (2008) J Christopher Fritton et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Pathogenesis of Age-Related Osteoporosis: Impaired Mechano-Responsiveness of Bone Is Not the Culprit
- (2008) Olli V. Leppänen et al. PLoS One
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