Chemical Inhibition of Bacterial Protein Tyrosine Phosphatase Suppresses Capsule Production

Identification of Streptococcus pneumoniae Cps2C Residues That Affect Capsular Polysaccharide Polymerization, Cell Wall Ligation, and Cps2D Phosphorylation

(2011) J. P. Byrne et al.   JOURNAL OF BACTERIOLOGY

Synthesis of capsular polysaccharide at the division septum of Streptococcus pneumoniae is dependent on a bacterial tyrosine kinase

(2011) Mafalda X. Henriques et al.   MOLECULAR MICROBIOLOGY

A Variable Region within the Genome of Streptococcus pneumoniae Contributes to Strain-Strain Variation in Virulence

(2011) Richard M. Harvey et al.   PLoS One

Fascioquinols A–F: bioactive meroterpenes from a deep-water southern Australian marine sponge, Fasciospongia sp.

(2011) Hua Zhang et al.   TETRAHEDRON

Within-Host Competition Drives Selection for the Capsule Virulence Determinant of Streptococcus pneumoniae

(2010) Elena S. Lysenko et al.   CURRENT BIOLOGY

Membrane Topology and DNA-Binding Ability of the Streptococcal CpsA Protein

(2010) B. R. Hanson et al.   JOURNAL OF BACTERIOLOGY

Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export

(2010) Emmanuelle Bechet et al.   MOLECULAR MICROBIOLOGY

Anti-virulence strategies to combat bacteria-mediated disease

(2010) David A. Rasko et al.   NATURE REVIEWS DRUG DISCOVERY

Bacterial tyrosine-kinases: Structure–function analysis and therapeutic potential

(2009) Christophe Grangeasse et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Streptococcus pneumoniae Capsule Inhibits Complement Activity and Neutrophil Phagocytosis by Multiple Mechanisms

(2009) C. Hyams et al.   INFECTION AND IMMUNITY

Crystal Structures of Wzb of Escherichia coli and CpsB of Streptococcus pneumoniae, Representatives of Two Families of Tyrosine Phosphatases that Regulate Capsule Assembly

(2009) Gregor Hagelueken et al.   JOURNAL OF MOLECULAR BIOLOGY

Pivotal Roles of the Outer Membrane Polysaccharide Export and Polysaccharide Copolymerase Protein Families in Export of Extracellular Polysaccharides in Gram-Negative Bacteria

(2009) L. Cuthbertson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Characterization and site-directed mutagenesis of Wzb, an O-phosphatase from Lactobacillus rhamnosus

(2008) Gisele LaPointe et al.   BMC BIOCHEMISTRY

Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

(2008) Helen W. Boucher et al.   CLINICAL INFECTIOUS DISEASES

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

(2008) Aras Kadioglu et al.   NATURE REVIEWS MICROBIOLOGY

Tuning Escherichia coli for membrane protein overexpression

(2008) S. Wagner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence-structure relationships in polysaccharide co-polymerase (PCP) proteins

(2008) Renato Morona et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structural Basis for the Regulation Mechanism of the Tyrosine Kinase CapB from Staphylococcus aureus

(2008) Vanesa Olivares-Illana et al.   PLOS BIOLOGY