Sialyl Residues Modulate LPS-Mediated Signaling through the Toll-Like Receptor 4 Complex

Functional Activity of MD-2 Polymorphic Variant Is Significantly Different in Soluble and TLR4-Bound Forms: Decreased Endotoxin Binding by G56R MD-2 and Its Rescue by TLR4 Ectodomain

(2014) Jožica Vašl et al.   JOURNAL OF IMMUNOLOGY

Differential Activation of Human TLR4 by Escherichia coli and Shigella flexneri 2a Lipopolysaccharide: Combined Effects of Lipid A Acylation State and TLR4 Polymorphisms on Signaling

(2014) P. Rallabhandi et al.   JOURNAL OF IMMUNOLOGY

Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics

(2011) Jean-Laurent Casanova et al.   Annual Review of Immunology

Endogenous PMN sialidase activity exposes activation epitope on CD11b/CD18 which enhances its binding interaction with ICAM-1

(2011) Chiguang Feng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

LPS-induced cytokine production in human dendritic cells is regulated by sialidase activity

(2010) Nicholas M. Stamatos et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Neu1 desialylation of sialyl α-2,3-linked β-galactosyl residues of TOLL-like receptor 4 is essential for receptor activation and cellular signaling

(2009) Schammim Ray Amith et al.   CELLULAR SIGNALLING

Dependence of pathogen molecule-induced Toll-like receptor activation and cell function on Neu1 sialidase

(2009) Schammim Ray Amith et al.   GLYCOCONJUGATE JOURNAL

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

Roles of galectins in infection

(2009) Gerardo R. Vasta   NATURE REVIEWS MICROBIOLOGY

Neuraminidase-1, a Subunit of the Cell Surface Elastin Receptor, Desialylates and Functionally Inactivates Adjacent Receptors Interacting with the Mitogenic Growth Factors PDGF-BB and IGF-2

(2008) Aleksander Hinek et al.   AMERICAN JOURNAL OF PATHOLOGY

Isolation of Monomeric and Dimeric Secreted MD-2

(2008) Athmane Teghanemt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Expression of sialyltransferase activity on intact human neutrophils

(2008) Salahaldin Rifat et al.   JOURNAL OF LEUKOCYTE BIOLOGY