Scalable Purification and Characterization of the Anticancer Lunasin Peptide from Soybean

Lunasin potentiates the effect of oxaliplatin preventing outgrowth of colon cancer metastasis, binds to α5β1 integrin and suppresses FAK/ERK/NF-κB signaling

(2011) Vermont P. Dia et al.   CANCER LETTERS

Lunasin induces apoptosis and modifies the expression of genes associated with extracellular matrix and cell adhesion in human metastatic colon cancer cells

(2011) Vermont P. Dia et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Relationship between lunasin's sequence and its inhibitory activity of histones H3 and H4 acetylation

(2011) Blanca Hernández-Ledesma et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Differential Expression of Thrombospondin (THBS1) in Tumorigenic and Nontumorigenic Prostate Epithelial Cells in Response to a Chromatin-Binding Soy Peptide

(2011) Alfredo F. Galvez et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Differential gene expression of RAW 264.7 macrophages in response to the RGD peptide lunasin with and without lipopolysaccharide stimulation

(2011) Vermont P. Dia et al.   PEPTIDES

Lunasin peptide purified from Solanum nigrum L. protects DNA from oxidative damage by suppressing the generation of hydroxyl radical via blocking fenton reaction

(2010) Jin Boo Jeong et al.   CANCER LETTERS

Lunasin promotes apoptosis in human colon cancer cells by mitochondrial pathway activation and induction of nuclear clusterin expression

(2010) Vermont P. Dia et al.   CANCER LETTERS

Lunasin, a novel seed peptide, sensitizes human breast cancer MDA-MB-231 cells to aspirin-arrested cell cycle and induced apoptosis

(2010) Chia-Chien Hsieh et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Amaranth lunasin-like peptide internalizes into the cell nucleus and inhibits chemical carcinogen-induced transformation of NIH-3T3 cells

(2010) Enrique Maldonado-Cervantes et al.   PEPTIDES

Complementary Roles in Cancer Prevention: Protease Inhibitor Makes the Cancer Preventive Peptide Lunasin Bioavailable

(2010) Chia-Chien Hsieh et al.   PLoS One

Antioxidant and anti-inflammatory properties of cancer preventive peptide lunasin in RAW 264.7 macrophages

(2009) Blanca Hernández-Ledesma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lunasin, with an arginine-glycine-aspartic acid motif, causes apoptosis to L1210 leukemia cells by activation of caspase-3

(2009) Elvira Gonzalez de Mejia et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Lunasin and lunasin-like peptides inhibit inflammation through suppression of NF-κB pathway in the macrophage

(2009) Elvira Gonzalez de Mejia et al.   PEPTIDES

Isolation, purification and characterisation of lunasin from defatted soybean flour and in vitro evaluation of its anti-inflammatory activity

(2008) V.P. Dia et al.   FOOD CHEMISTRY

Bowman−Birk Inhibitor and Genistein among Soy Compounds That Synergistically Inhibit Nitric Oxide and Prostaglandin E2Pathways in Lipopolysaccharide-Induced Macrophages

(2008) Vermont P. Dia et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Bioactive Peptides in Amaranth (Amaranthus hypochondriacus) Seed

(2008) C. Silva-Sánchez et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Lunasin, a novel seed peptide for cancer prevention

(2008) Blanca Hernández-Ledesma et al.   PEPTIDES