Small-Molecule Synthetic Compound Norcantharidin Reverses Multi-Drug Resistance by Regulating Sonic Hedgehog Signaling in Human Breast Cancer Cells

Somatic mutations in the notch, NF-KB, PIK3CA, and hedgehog pathways in human breast cancers

(2012) Xiang Jiao et al.   GENES CHROMOSOMES & CANCER

Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer

(2011) Y. A. Yoo et al.   CANCER RESEARCH

Small Molecule Inhibition of GDC-0449 Refractory Smoothened Mutants and Downstream Mechanisms of Drug Resistance

(2010) Gerrit J. P. Dijkgraaf et al.   CANCER RESEARCH

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway

(2010) Elspeth M. Beauchamp et al.   JOURNAL OF CLINICAL INVESTIGATION

Review: Targeting the Hedgehog pathway in cancer

(2010) Sachin Gupta et al.   Therapeutic Advances in Medical Oncology

Norcantharidin induces anoikis through Jun-N-terminal kinase activation in CT26 colorectal cancer cells

(2009) Yu-Jen Chen et al.   ANTI-CANCER DRUGS

A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells

(2009) Yu-Jen Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Norcantharidin is a small-molecule synthetic compound with anti-angiogenesis effect

(2009) Yu-Jen Chen et al.   LIFE SCIENCES

Cantharidin reverses multidrug resistance of human hepatoma HepG2/ADM cells via down-regulation of P-glycoprotein expression

(2008) Li Hua Zheng et al.   CANCER LETTERS

Combination of imatinib and vinorelbine enhances cell growth inhibition in breast cancer cells via PDGFR β signalling

(2008) Marion T. Weigel et al.   CANCER LETTERS