An in vivo cis-Regulatory Screen at the Type 2 Diabetes Associated TCF7L2 Locus Identifies Multiple Tissue-Specific Enhancers

Transcriptional enhancers in development and disease

(2012) Noboru Sakabe et al.   GENOME BIOLOGY

At-Risk Variant in TCF7L2 for Type II Diabetes Increases Risk of Schizophrenia

(2011) Thomas Hansen et al.   BIOLOGICAL PSYCHIATRY

Chromatin occupancy of transcription factor 7-like 2 (TCF7L2) and its role in hepatic glucose metabolism

(2011) L. Norton et al.   DIABETOLOGIA

Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism

(2011) D. Savic et al.   GENOME RESEARCH

Modulation of Tcf7l2 Expression Alters Behavior in Mice

(2011) Daniel Savic et al.   PLoS One

The ghrelin O-acyltransferase–ghrelin system: a novel regulator of glucose metabolism

(2011) Kristy M Heppner et al.   Current Opinion in Endocrinology Diabetes and Obesity

Insulin Signaling in Osteoblasts Integrates Bone Remodeling and Energy Metabolism

(2010) Mathieu Ferron et al.   CELL

Global Epigenomic Analysis of Primary Human Pancreatic Islets Provides Insights into Type 2 Diabetes Susceptibility Loci

(2010) Michael L. Stitzel et al.   Cell Metabolism

A map of open chromatin in human pancreatic islets

(2010) Kyle J Gaulton et al.   NATURE GENETICS

Rethinking the genetic basis for comorbidity of schizophrenia and type 2 diabetes

(2010) P.I. Lin et al.   SCHIZOPHRENIA RESEARCH

Neonatal growth and regeneration of β-cells are regulated by the Wnt/β-catenin signaling in normal and diabetic rats

(2009) Florence Figeac et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Evidence for neuroendocrine function of a unique splicing form of TCF7L2 in human brain, islets and gut

(2009) L. Prokunina-Olsson et al.   DIABETOLOGIA

Is Wnt signalling the final common pathway leading to bone formation?

(2009) Frances Milat et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

TCF7L2 Polymorphism rs7903146 Is Associated with Coronary Artery Disease Severity and Mortality

(2009) André Gustavo P. Sousa et al.   PLoS One

Expression of the transcription factor 7-like 2 gene (TCF7L2) in human adipocytes is down regulated by insulin

(2008) Maja Ahlzén et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The transcription factor 7-like 2 gene and increased risk of type 2 diabetes: an update

(2008) Valeriya Lyssenko   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Variation in TCF7L2 and Increased Risk of Colon Cancer: The Atherosclerosis Risk in Communities (ARIC) Study

(2008) A. R. Folsom et al.   DIABETES CARE

A novel mode of enhancer evolution: The Tal1 stem cell enhancer recruited a MIR element to specifically boost its activity

(2008) A. M. Smith et al.   GENOME RESEARCH