The HyVac4 Subunit Vaccine Efficiently Boosts BCG-Primed Anti-Mycobacterial Protective Immunity

Multifunctional, High-Level Cytokine-Producing Th1 Cells in the Lung, but Not Spleen, Correlate with Protection against Mycobacterium tuberculosis Aerosol Challenge in Mice

(2014) E. K. Forbes et al.   JOURNAL OF IMMUNOLOGY

Prognostic Value of a T-Cell–Based, Interferon-γ Biomarker in Children with Tuberculosis Contact

(2013) Mustafa Bakir   ANNALS OF INTERNAL MEDICINE

Preclinical evidence for implementing a prime-boost vaccine strategy for tuberculosis

(2012) Michael J. Brennan et al.   VACCINE

First in humans: A new molecularly defined vaccine shows excellent safety and strong induction of long-livedMycobacterium tuberculosis-specific Th1-cell like responses

(2011) Tom H. M. Ottenhoff et al.   Human vaccines & immunotherapeutics

Functional Capacity of Mycobacterium tuberculosis-Specific T Cell Responses in Humans Is Associated with Mycobacterial Load

(2011) C. L. Day et al.   JOURNAL OF IMMUNOLOGY

A Booster Vaccine Expressing a Latency-Associated Antigen Augments BCG Induced Immunity and Confers Enhanced Protection against Tuberculosis

(2011) Bappaditya Dey et al.   PLoS One

Suboptimal Activation of Antigen-Specific CD4+ Effector Cells Enables Persistence of M. tuberculosis In Vivo

(2011) Tyler D. Bold et al.   PLoS Pathogens

Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

(2010) Benjamin M. N. Kagina et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Immunization of mice with mycobacterial culture filtrate proteins

(2010) R D. HUBBARD et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Multifunctional CD4+ T cells correlate with active Mycobacterium tuberculosis infection

(2010) Nadia Caccamo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Difference in TB10.4 T-cell epitope recognition following immunization with recombinant TB10.4, BCG or infection with Mycobacterium tuberculosis

(2010) Rolf Billeskov et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Evaluation of the Prognostic Value of IFN-γ Release Assay and Tuberculin Skin Test in Household Contacts of Infectious Tuberculosis Cases in Senegal

(2010) Christian Lienhardt et al.   PLoS One

Protection and Polyfunctional T Cells Induced by Ag85B-TB10.4/IC31® against Mycobacterium tuberculosis Is Highly Dependent on the Antigen Dose

(2009) Claus Aagaard et al.   PLoS One

Non-clinical efficacy and safety of HyVac4:IC31 vaccine administered in a BCG prime–boost regimen

(2009) Yasir A.W. Skeiky et al.   VACCINE

Immunogenicity and Protective Efficacy of Prime-Boost Regimens with Recombinant  ureC hly+ Mycobacterium bovis BCG and Modified Vaccinia Virus Ankara Expressing M. tuberculosis Antigen 85A against Murine Tuberculosis

(2008) E. Z. Tchilian et al.   INFECTION AND IMMUNITY

Genetic and Immunologic Heterogeneity among Persons Who Control HIV Infection in the Absence of Therapy

(2008) Florencia Pereyra et al.   JOURNAL OF INFECTIOUS DISEASES

Consequence of prior exposure to environmental mycobacteria on BCG vaccination and diagnosis of tuberculosis infection

(2008) Michelle Thom et al.   TUBERCULOSIS