Small, N-Terminal Tags Activate Parkin E3 Ubiquitin Ligase Activity by Disrupting Its Autoinhibited Conformation
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Title
Small, N-Terminal Tags Activate Parkin E3 Ubiquitin Ligase Activity by Disrupting Its Autoinhibited Conformation
Authors
Keywords
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Journal
PLoS One
Volume 7, Issue 4, Pages e34748
Publisher
Public Library of Science (PLoS)
Online
2012-04-05
DOI
10.1371/journal.pone.0034748
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Related references
Note: Only part of the references are listed.- Recent Advances in the Genetics of Parkinson's Disease
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- PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
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- Posttranslational Modifications as Versatile Regulators of Parkin Function
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- Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder
- (2011) Yuzuru Imai et al. CURRENT OPINION IN NEUROBIOLOGY
- Autoregulation of Parkin activity through its ubiquitin-like domain
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- Ataxin-3 Deubiquitination Is Coupled to Parkin Ubiquitination via E2 Ubiquitin-conjugating Enzyme
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- Parkin occurs in a stable, non-covalent, ∼110-kDa complex in brain
- (2010) Cindy Van Humbeeck et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy
- (2010) Matthew E. Gegg et al. HUMAN MOLECULAR GENETICS
- Parkin degrades estrogen-related receptors to limit the expression of monoamine oxidases
- (2010) Y. Ren et al. HUMAN MOLECULAR GENETICS
- Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients
- (2010) A. Rakovic et al. HUMAN MOLECULAR GENETICS
- The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
- (2010) Thomas M. Durcan et al. HUMAN MOLECULAR GENETICS
- PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
- (2010) Noriyuki Matsuda et al. JOURNAL OF CELL BIOLOGY
- The role of parkin in familial and sporadic Parkinson's disease
- (2010) Ted M. Dawson et al. MOVEMENT DISORDERS
- PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
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- Mechanisms of mitophagy
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- Genetic Analysis of Pathways to Parkinson Disease
- (2010) John Hardy NEURON
- Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function
- (2010) H. S. Ko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phosphorylation of parkin by Parkinson disease-linked kinase PINK1 activates parkin E3 ligase function and NF- B signaling
- (2009) D. Sha et al. HUMAN MOLECULAR GENETICS
- PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
- (2009) C. Vives-Bauza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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