Large-Scale Phenotyping of an Accurate Genetic Mouse Model of JNCL Identifies Novel Early Pathology Outside the Central Nervous System

The juvenile Batten disease protein, CLN3, and its role in regulating anterograde and retrograde post-Golgi trafficking

(2012) Susan L Cotman et al.   Clinical Lipidology

Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes

(2011) Arno Hänninen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The yeast Batten disease orthologue Btn1 controls endosome–Golgi retrograde transport via SNARE assembly

(2011) Rachel Kama et al.   JOURNAL OF CELL BIOLOGY

Females experience a more severe disease course in batten disease

(2011) Jennifer Cialone et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Distinct Mechanisms of Ferritin Delivery to Lysosomes in Iron-Depleted and Iron-Replete Cells

(2011) T. Asano et al.   MOLECULAR AND CELLULAR BIOLOGY

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(2011) Anne-Helene Lebrun et al.   MOLECULAR MEDICINE

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Altered sensitivity of cerebellar granule cells to glutamate receptor overactivation in the Cln3Δex7/8-knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

(2011) Rozzy Finn et al.   NEUROCHEMISTRY INTERNATIONAL

Cardiac involvement in juvenile neuronal ceroid lipofuscinosis (Batten disease)

(2011) J. R. Ostergaard et al.   NEUROLOGY

Distinct Early Molecular Responses to Mutations Causing vLINCL and JNCL Presage ATP Synthase Subunit C Accumulation in Cerebellar Cells

(2011) Yi Cao et al.   PLoS One

Mouse phenotyping

(2010) Helmut Fuchs et al.   METHODS

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Chronic Murine Typhoid Fever Is a Natural Model of Secondary Hemophagocytic Lymphohistiocytosis

(2010) Diane E. Brown et al.   PLoS One

Identification ofAtg5-dependent transcriptional changes and increases in mitochondrial mass inAtg5-deficient T lymphocytes

(2009) Linda M. Stephenson et al.   Autophagy

Towards understanding the neuronal ceroid lipofuscinoses

(2009) Alfried Kohlschütter et al.   BRAIN & DEVELOPMENT

The German Mouse Clinic: A Platform for Systemic Phenotype Analysis of Mouse Models

(2009) H. Fuchs et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Neurodevelopmental delay in theCln3Δex7/8mouse model for Batten disease

(2009) N. S. Osório et al.   GENES BRAIN AND BEHAVIOR

Molecular correlates of axonal and synaptic pathology in mouse models of Batten disease

(2009) C. Kielar et al.   HUMAN MOLECULAR GENETICS

S. pombe btn1, the orthologue of the Batten disease gene CLN3, is required for vacuole protein sorting of Cpy1p and Golgi exit of Vps10p

(2009) S. Codlin et al.   JOURNAL OF CELL SCIENCE

Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk

(2009) W. W. C. Shum et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Synaptic Changes in the Thalamocortical System of Cathepsin D-Deficient Mice

(2009) Sanna Partanen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Agouti C57BL/6N embryonic stem cells for mouse genetic resources

(2009) Stephen J Pettitt et al.   NATURE METHODS

Neuronal ceroid lipofuscinoses

(2008) Anu Jalanko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

btn1 affects cytokinesis and cell-wall deposition by independent mechanisms, one of which is linked to dysregulation of vacuole pH

(2008) S. Codlin et al.   JOURNAL OF CELL SCIENCE

Lysosomal Activity Associated with Developmental Axon Pruning

(2008) J. W. Song et al.   JOURNAL OF NEUROSCIENCE

Developmental impairments of select neurotransmitter systems in brains ofCln3Δex7/8 knock-in mice, an animal model of juvenile neuronal ceroid lipofuscinosis

(2008) Philipp Herrmann et al.   JOURNAL OF NEUROSCIENCE RESEARCH

CLN3p Impacts Galactosylceramide Transport, Raft Morphology, and Lipid Content

(2008) Elena Rusyn et al.   PEDIATRIC RESEARCH

Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages

(2008) Stefka B. Petkova et al.   PHYSIOLOGICAL GENOMICS

Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study

(2008) Silvia Mandillo et al.   PHYSIOLOGICAL GENOMICS

Phenotypic characterization of a mouse model of juvenile neuronal ceroid lipofuscinosis

(2007) Martin L. Katz et al.   NEUROBIOLOGY OF DISEASE

Identification of α-fetoprotein as an autoantigen in juvenile Batten disease

(2007) Julian A. Castaneda et al.   NEUROBIOLOGY OF DISEASE