The Tyrphostin Agent AG490 Prevents and Reverses Type 1 Diabetes in NOD Mice

Genetic Analysis of Adult-Onset Autoimmune Diabetes

(2011) J. M. M. Howson et al.   DIABETES

Trying to Reset the Clock on Type 1 Diabetes

(2011) J. Couzin-Frankel   SCIENCE

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

(2011) Vincent Plagnol et al.   PLoS Genetics

JAK2 inhibitors: What's the true therapeutic potential?

(2010) Fabio P.S. Santos et al.   BLOOD REVIEWS

Tyrphostins as Potential Therapeutic Agents for Acute Kidney Injury

(2010) S. Goncalves et al.   CURRENT MEDICINAL CHEMISTRY

Safety and Efficacy of INCB018424, a JAK1 and JAK2 Inhibitor, in Myelofibrosis

(2010) Srdan Verstovsek et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 2 study of CEP-701, an orally available JAK2 inhibitor, in patients with primary or post-polycythemia vera/essential thrombocythemia myelofibrosis

(2009) F. P. S. Santos et al.   BLOOD

M-CSF and GM-CSF Regulation of STAT5 Activation and DNA Binding in Myeloid Cell Differentiation is Disrupted in Nonobese Diabetic Mice

(2009) B. Rumore-Maton et al.   Clinical & Developmental Immunology

Potential utility of small tyrosine kinase inhibitors in the treatment of diabetes

(2009) Dariush Mokhtari et al.   CLINICAL SCIENCE

Ciliary neurotrophic factor (CNTF) signals through STAT3–SOCS3 pathway and protects rat pancreatic islets from cytokine-induced apoptosis

(2009) Luiz F. Rezende et al.   CYTOKINE

Immune Depletion With Cellular Mobilization Imparts Immunoregulation and Reverses Autoimmune Diabetes in Nonobese Diabetic Mice

(2009) M. J. Parker et al.   DIABETES

Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families

(2009) J M M Howson et al.   GENES AND IMMUNITY

Janus kinases in immune cell signaling

(2009) Kamran Ghoreschi et al.   IMMUNOLOGICAL REVIEWS

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Phase 1 Dose-Escalation Study of CP-690 550 in Stable Renal Allograft Recipients: Preliminary Findings of Safety, Tolerability, Effects on Lymphocyte Subsets and Pharmacokinetics

(2008) E. van Gurp et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Enhanced Expression of Janus Kinase-Signal Transducer and Activator of Transcription Pathway Members in Human Diabetic Nephropathy

(2008) C. C. Berthier et al.   DIABETES

Combination Therapy With Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice

(2008) W. L. Suarez-Pinzon et al.   DIABETES

GM-CSF induces STAT5 binding at epigenetic regulatory sites within the Csf2 promoter of non-obese diabetic (NOD) mouse myeloid cells

(2008) F. Seydel et al.   JOURNAL OF AUTOIMMUNITY

Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice

(2008) C. Louvet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA