Bone Marrow p16INK4a-Deficiency Does Not Modulate Obesity, Glucose Homeostasis or Atherosclerosis Development

Overexpression of the Cell Cycle Inhibitor p16 INK4a Promotes a Prothrombotic Phenotype Following Vascular Injury in Mice

(2011) Jessica C. Cardenas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cdkn2a Is an Atherosclerosis Modifier Locus That Regulates Monocyte/Macrophage Proliferation

(2011) Chao-Ling Kuo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages

(2011) C. Cudejko et al.   BLOOD

Human Atherosclerotic Plaque Alternative Macrophages Display Low Cholesterol Handling but High Phagocytosis Because of Distinct Activities of the PPARγ and LXRα Pathways

(2011) Giulia Chinetti-Gbaguidi et al.   CIRCULATION RESEARCH

Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype

(2011) L. Fuentes et al.   DIABETOLOGIA

Coronary Artery Calcification and Its Relationship to Validated Genetic Variants for Diabetes Mellitus Assessed in the Heinz Nixdorf Recall Cohort

(2010) Sonali Pechlivanis et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chromosome 9p21 and coronary risk – The mystery continues

(2010) Patrick Linsel-Nitschke et al.   ATHEROSCLEROSIS

Expression of Chr9p21 genes CDKN2B (p15INK4b), CDKN2A (p16INK4a, p14ARF) and MTAP in human atherosclerotic plaque

(2010) Lesca Miriam Holdt et al.   ATHEROSCLEROSIS

p19ARFDeficiency Reduces Macrophage and Vascular Smooth Muscle Cell Apoptosis and Aggravates Atherosclerosis

(2010) Herminia González-Navarro et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice

(2010) Axel Visel et al.   NATURE

Chromosome 9p21 and Coronary Artery Disease

(2010) Ruth McPherson   NEW ENGLAND JOURNAL OF MEDICINE

The emerging genetics of type 2 diabetes

(2010) Amélie Bonnefond et al.   TRENDS IN MOLECULAR MEDICINE

Chromosome 9p21 SNPs Associated with Multiple Disease Phenotypes Correlate with ANRIL Expression

(2010) Michael S. Cunnington et al.   PLoS Genetics

Interferon γ Attenuates Insulin Signaling, Lipid Storage, and Differentiation in Human Adipocytes via Activation of the JAK/STAT Pathway

(2009) Fiona C. McGillicuddy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The CDK4–pRB–E2F1 pathway controls insulin secretion

(2009) Jean-Sébastien Annicotte et al.   NATURE CELL BIOLOGY

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

T-lymphocyte Infiltration in Visceral Adipose Tissue

(2008) Ulrich Kintscher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

PPARδ/β: The Lobbyist Switching Macrophage Allegiance in Favor of Metabolism

(2008) Béatrice Desvergne   Cell Metabolism

Translating molecular discoveries into new therapies for atherosclerosis

(2008) Daniel J. Rader et al.   NATURE