Kindlins, Integrin Activation and the Regulation of Talin Recruitment to αIIbβ3

Kindlin

(2011) Feng Ye et al.   CURRENT OPINION IN HEMATOLOGY

Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins

(2011) H. Qu et al.   JOURNAL OF CELL SCIENCE

Membrane Binding of the N-Terminal Ubiquitin-Like Domain of kindlin-2 Is Crucial for Its Regulation of Integrin Activation

(2011) H. Dhanuja Perera et al.   STRUCTURE

An improved bimolecular fluorescence complementation assay with a high signal-to-noise ratio

(2010) Yutaka Kodama* et al.   BIOTECHNIQUES

Kindlins in FERM adhesion

(2010) N. L. Malinin et al.   BLOOD

Tyrosine Phosphorylation of Integrin β3Regulates Kindlin-2 Binding and Integrin Activation

(2010) Kamila Bledzka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Integrin Co-activator Kindlin-3 Is Expressed and Functional in a Non-hematopoietic Cell, the Endothelial Cell

(2010) Katarzyna Bialkowska et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recreation of the terminal events in physiological integrin activation

(2010) Feng Ye et al.   JOURNAL OF CELL BIOLOGY

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma

(2010) S. Ammoun et al.   NEURO-ONCOLOGY

The Structure of the Talin/Integrin Complex at a Lipid Bilayer: An NMR and MD Simulation Study

(2010) Antreas C. Kalli et al.   STRUCTURE

High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53 - NF-kappaB - complex-dependent gene expression in human heart failure

(2010) Mun-Kit Choy et al.   Genome Medicine

How ILK and kindlins cooperate to orchestrate integrin signaling

(2009) Ralph T Böttcher et al.   CURRENT OPINION IN CELL BIOLOGY

The structure of an integrin/talin complex reveals the basis of inside-out signal transduction

(2009) Nicholas J Anthis et al.   EMBO JOURNAL

The structure of the integrin αIIbβ3 transmembrane complex explains integrin transmembrane signalling

(2009) Tong-Lay Lau et al.   EMBO JOURNAL

Kindlin-1 and -2 Directly Bind the C-terminal Region of β Integrin Cytoplasmic Tails and Exert Integrin-specific Activation Effects

(2009) David S. Harburger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Structure of an Interdomain Complex That Regulates Talin Activity

(2009) Benjamin T. Goult et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integrin signalling at a glance

(2009) D. S. Harburger et al.   JOURNAL OF CELL SCIENCE

Kindlin-3 is required for β2 integrin–mediated leukocyte adhesion to endothelial cells

(2009) Markus Moser et al.   NATURE MEDICINE

The Tail of Integrins, Talin, and Kindlins

(2009) M. Moser et al.   SCIENCE

CalDAG-GEFI and protein kinase C represent alternative pathways leading to activation of integrin  IIb 3 in platelets

(2008) S. M. Cifuni et al.   BLOOD

RIAM Activates Integrins by Linking Talin to Ras GTPase Membrane-targeting Sequences

(2008) Ho-Sup Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3

(2008) Naohide Watanabe et al.   JOURNAL OF CELL BIOLOGY

Kindlin-2 (Mig-2): a co-activator of β3integrins

(2008) Yan-Qing Ma et al.   JOURNAL OF CELL BIOLOGY

Bimolecular fluorescence complementation (BiFC) analysis of protein interactions in Caenorhabditis elegans

(2008) Susan M. Hiatt et al.   METHODS

Structural Basis for the Autoinhibition of Talin in Regulating Integrin Activation

(2008) Esen Goksoy et al.   MOLECULAR CELL

Kindlin-3 is essential for integrin activation and platelet aggregation

(2008) Markus Moser et al.   NATURE MEDICINE